Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping
Tuberculosis Genotyping Network, United States
Molecular Epidemiology of Multidrug-Resistant Tuberculosis, New York City, 1995–1997
Table 1
MDR (n=241) | Non-MDR (n=4,714) | ||||
---|---|---|---|---|---|
Characteristic | No. | % | No. | % | p value |
Yr of diagnosis | |||||
1995 | 106 | 44.0 | 1,816 | 38.5 | 0.0898 |
1996 | 81 | 33.6 | 1,586 | 33.6 | 0.9912 |
1997 | 54 | 22.4 | 1,312 | 27.8 | 0.0660 |
Median age (range), yrs | 41 (5–85) | 41 (0–100) | 0.3071 | ||
Male sex | 147 | 61.0 | 3,020 | 64.1 | 0.3333 |
U.S.-born | 166 | 68.9 | 2,483 | 52.7 | <0.001 |
HIV serostatus | |||||
Positive | 128 | 53.1 | 1,478 | 31.4 | <0.001 |
Negative | 75 | 31.2 | 1,759 | 37.3 | 0.0521 |
Unknown | 38 | 15.8 | 1,477 | 31.3 | <0.001 |
Race/ethnicity | |||||
Asian | 24 | 10.0 | 817 | 17.3 | 0.0029 |
Hispanic | 75 | 31.1 | 1,266 | 26.9 | 0.1461 |
Black non-Hispanic | 105 | 43.6 | 2,089 | 44.3 | 0.8200 |
White non-Hispanic | 37 | 15.4 | 542 | 11.5 | 0.0692 |
Health-care worker | 15 | 6.2 | 109 | 2.3 | 0.0001 |
Homeless | 28 | 11.6 | 344 | 7.3 | 0.0130 |
Injection drug user | 33 | 13.7 | 275 | 5.8 | <0.001 |
Disease site | |||||
Pulmonary only | 176 | 73.0 | 3,397 | 72.1 | 0.7440 |
Extra-pulmonary only | 35 | 14.5 | 894 | 19.0 | 0.0848 |
Pulmonary + extra-pulmonary | 30 | 12.5 | 423 | 9.0 | 0.0679 |
Specimen AFB smear-positivea | 141 | 68.5 | 2,129 | 55.7 | 0.0003 |
Cavitary lesion(s)b | 47 | 22.8 | 740 | 19.4 | 0.2247 |
aRespiratory specimen during the 30 days after initial specimen for bacteriologic test was taken. Excludes those who had only extrapulmonary disease.
bExcludes those with extrapulmonary disease only.
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