Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping
Tuberculosis Genotyping Network, United States
Statewide Molecular Epidemiology of Mycobacterium tuberculosis Transmission in a Moderate- to Low-Incidence State: Are Contact Investigations Enough?
Wendy A. Cronin*
, Jonathan E. Golub*, Monica J. Lathan†, Leonard N. Mukasa*, Nancy Hooper*, Jafar H. Razeq*, Nancy G. Baruch*, Donna Mulcahy‡, William H. Benjamin§, Laurence S. Magder¶, G. Thomas Strickland¶, and William R. Bishai#
, Jonathan E. Golub*, Monica J. Lathan†, Leonard N. Mukasa*, Nancy Hooper*, Jafar H. Razeq*, Nancy G. Baruch*, Donna Mulcahy‡, William H. Benjamin§, Laurence S. Magder¶, G. Thomas Strickland¶, and William R. Bishai#
Table 2
Selected characteristics of culture-positive patients with comparison between categories
| No. patients with recent TB (%)
(N=115) |
No. patients with probable
recent TB (%)
(n=82) |
No. patients with reactivated TB (%)
(n=788) |
p value |
p value |
|
|---|---|---|---|---|---|
| Characteristic | Group A | Group B | Group C | A vs. B | A vs. C |
| Residence | |||||
| Baltimore City | 57 (50.0) | 38 (46.3) | 157 (19.9) | 0.66 | <0.001 |
| Other state jurisdictions | 58 (50.0) | 44 (53.7) | 631 (80.1) | ||
| Age group (yrs) | |||||
| 0–14a | 6 (5.2) | 3 (3.7) | 5 (0.6) | <0.001 | <0.001 |
| 15–24 | 21 (18.3) | 7 (8.5) | 86 (10.9) | ||
| 25–44 | 46 (40.0) | 27 (32.9) | 275 (34.9) | ||
| 45–64 | 33 (28.7) | 20 (24.3) | 178 (22.6) | ||
| >65 | 9 (7.8) | 25 (30.4) | 244 (31.0) | ||
| Race/ethnicity | |||||
| White, non-Hispanic | 20 (17.4) | 17 (20.7) | 162 (20.6) | 0.03 | <0.001 |
| Black, non-Hispanic | 89 (77.4) | 51 (62.2) | 341 (43.3) | ||
| Hispanic | 1 (0.9) | 5 (6.1) | 84 (10.7) | ||
| Asian | 5 (4.3) | 9 (11.0) | 200 (25.4) | ||
| Native American | 0 | 0 | 1 (0.1) | ||
| Country of birth | |||||
| United States | 105 (91.3) | 66 (80.5) | 360 (45.7) | 0.03 | <0.001 |
| Other | 10 (8.7) | 16 (19.5) | 428 (54.3) | ||
| Long-term care resident | |||||
| Yes | 7 (6.1) | 5 (3.3) | 25 (3.2) | 1.00 | 0.11 |
| No | 108 (93.9) | 77 (96.7) | 763 (96.8) | ||
| Homeless | |||||
| Yes | 18 (15.7) | 8 (9.8) | 23 (2.9) | 0.22 | <0.001 |
| No | 97 (84.3) | 74 (90.2) | 765 (97.1) | ||
| Prison resident | |||||
| Yes | 13 (11.3) | 10 (13.1) | 21 (2.7) | 0.85 | <0.001 |
| No | 102 (88.7) | 72 (86.9) | 767 (97.3) | ||
| Uses illegal drugs or abuses alcohol | |||||
| Yes | 53 (46.0) | 30 (36.6) | 76 (9.6) | 0.18 | <0.001 |
| No | 62 (54.0) | 58 (63.4) | 712 (90.4) | ||
| HIV-infected | |||||
| Yes | 28 (24.3) | 19 (23.2) | 75 (9.5) | 0.85 | <0.001 |
| No |
87 (75.7) |
63 (76.8) |
713 (90.5) |
||
| aIncludes one child < 6 years old without a known source patient; the case was classified as recent based on age. | |||||
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