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Volume 9, Number 6—June 2003
Synopsis

Inactivation of Bacillus anthracis Spores

Ellen A. Spotts Whitney*, Mark E. Beatty*, Thomas H. Taylor*, Robbin Weyant*, Jeremy Sobel*, Matthew J. Arduino*, and David A. Ashford*Comments to Author 
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 1

Heat inactivation of B. anthracis sporesa

Temperature Time Inoculum size Inactivation effect Ref.
Boiling
100°C
 10 min
 3 x 106
 Sample sterilized
 4,5
5 min
 7.5 x 108
 Sample sterilized
Moist heat
90°C
 20 min
 1.2 x 106
 Sample sterilized
 4,5
90°C to 91°C
 60 min
 3 x 108
 Spores detected
100°C
 10 min
 1.2 x 106
 Sample sterilized
 5,6
100°C to 101°C
 17 min
 1 x 105
 Sample sterilized
105°C
 10 min
 3 x 106
 Sample sterilized
 5
120°C
 15 min
 2.4 x 108
 Sample sterilized
 4
Dry heat
140°C
 >90 min
 6 x 103 to 1.2 x 104
 Sample sterilized
 7
150°C
 10 min
 6 x 103 to 1.2 x 104
 Sample sterilized
160°C
 10 min
 6 x 103 to 1.2 x 104
 Sample sterilized
180°C
 2 min
 6 x 103 to 1.2 x 104
 Sample sterilized
190°C
 1 min
 6 x 103 to 1.2 x 104
 Sample sterilized
200°C 30 sec 6 x 103 to 1.2 x 104 Sample sterilized

aSpores in liquid suspension exposed to flowing steam at 100°C.

Main Article

Page created: December 21, 2010
Page updated: December 21, 2010
Page reviewed: December 21, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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