Volume 9, Number 6—June 2003
Research
Clinical Implications of Varying Degrees of Vancomycin Susceptilibity in Methicillin-Resistant Staphylococcus aureus Bacteremia1
Mitchell J. Schwaber*†‡
, Sharon B. Wright*†, Yehuda Carmeli*†‡, Lata Venkataraman*†, Paola C. DeGirolami*†, Aneta Gramatikova§, Trish M. Perl§, George Sakoulas*†, and Howard S. Gold*†
, Sharon B. Wright*†, Yehuda Carmeli*†‡, Lata Venkataraman*†, Paola C. DeGirolami*†, Aneta Gramatikova§, Trish M. Perl§, George Sakoulas*†, and Howard S. Gold*†
Table 2
Descriptive characteristics of cohort
| Characteristic | Cases, n=61 (%) | Controls, n=8 (%) | p | |
|---|---|---|---|---|
| Mean age (y) |
61±17 |
64±14 |
0.21 |
|
| Male |
37 (61) |
53 (60) |
1.00 |
|
| Diabetes mellitus |
30 (49) |
34 (39) |
0.24 |
|
| Renal disease |
20 (33) |
29 (33) |
1.00 |
|
| Hemodialysis |
10 (16) |
12 (14) |
0.65 |
|
| Cardiovascular disease |
41 (67) |
56 (64) |
0.73 |
|
| Pulmonary disease |
19 (31) |
35 (40) |
0.30 |
|
| Hepatic disease |
8 (13) |
7 (8) |
0.41 |
|
| HIV |
3 (5) |
3 (3) |
0.69 |
|
| Prosthetic joint or valve, or permanent pacemaker |
13 (21) |
11 (13) |
0.18 |
|
| Hospitalization at same institution
<30 days preceding culture |
51 (84) |
66 (75) |
0.23 |
|
| Surgery during admission before culture |
17 (28) |
20 (23) |
0.56 |
|
| Intensive care unit stay during admission before culture |
33 (54) |
38 (43) |
0.24 |
|
| Severity of illness scorea | 0.62 | |||
aSeverity of illness is based on modified McCabe criteria (23): 1, severe underlying coexisting chronic condition at imminent risk of death; 2, significant underlying coexisting chronic condition, not at imminent risk of death; 3, no significant underlying coexisting chronic condition.
1Presented in part at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, Illinois, December 2001.
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