Volume 9, Number 8—August 2003
Research
Multidrug-Resistant Tuberculosis in HIV-Negative Patients, Buenos Aires, Argentina
Domingo Palmero*
, Viviana Ritacco†, Martha Ambroggi‡, Marcela Natiello‡, Lucía Barrera†, Lilian Capone‡, Alicia Dambrosi‡, Martha Di Lonardo‡, Nélida Isola‡, Susana Poggi‡, Marisa Vescovo‡, and Eduardo Abbate‡
, Viviana Ritacco†, Martha Ambroggi‡, Marcela Natiello‡, Lucía Barrera†, Lilian Capone‡, Alicia Dambrosi‡, Martha Di Lonardo‡, Nélida Isola‡, Susana Poggi‡, Marisa Vescovo‡, and Eduardo Abbate‡
Table 1
Demographic, clinical, and bacteriologic features of acquired versus initial multidrug-resistant tuberculosis (MDRTB) cases among 291 HIV-negative patients, Muñiz Hospital, Argentina, 1991–2000
| Acquired MDRTB (n=212) | Initial MDRTB (n=79) | p value | |
|---|---|---|---|
| Age (y ± SD) |
39.8±13.2 |
35.3±15.0 |
0.013 |
| Gender (male/female) |
125/87 |
32/47 |
0.005 |
| Origin (Argentinean/foreign-born)a |
180/32 |
64/15 |
0.533 |
| Chest x-ray (minimal/moderate/advanced) |
2/52/158 |
10/38/31 |
<0.0001 |
| Underlying illness (Y/N) |
46/166 |
15/64 |
0.731 |
| Diabetes (N) |
26 |
7 |
– |
| Alcoholism (N) |
9 |
1 |
– |
| Silicosis (N) |
2 |
1 |
– |
| Steroid treatment (N) |
2 |
3 |
– |
| Substance abuse (N) |
1 |
0 |
– |
| Malignancy (N) |
1 |
2 |
– |
| Other (N) |
5 |
1 |
– |
| Drug resistance, median number of drugs (range) | 4 (2–8) | 4 (2–6) | – |
aNeighboring countries (Peru, Bolivia, Paraguay).
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