Figure 1. . CD3 (A) and CD4 (B) cells immunostained with diaminobenzidine and horseradish peroxidase in lymph node biopsy sample from patient 2 (Aus-GM). Original magnification ×40. C) Peripheral blood cells smear from adult T-lymphocytic leukemia patient 1 (Aus-NR). Tumor cells exhibiting multilobulated nuclei (or flower cells), which are mature activated CD4+ T-lymphocytes. D) Contrast-enhanced computed tomographic image of abdomen of patient 1, revealing para-aortic lymphadenopathy. E) Contrast-enhanced computed tomographic image of patient 1, showing lytic bone lesion (L-1 veretebral body) with soft tissue involvement (arrow).