Volume 10, Number 1—January 2004
Research
Experimental Infection of Cats and Dogs with West Nile Virus
Laura E. Austgen*, Richard A. Bowen*
, Michel L. Bunning†, Brent S. Davis†, Carl J. Mitchell†, and Gwong-Jen J. Chang†
, Michel L. Bunning†, Brent S. Davis†, Carl J. Mitchell†, and Gwong-Jen J. Chang†
Table
West Nile virus titers in serum of dogs and cats following bites of virus-infected mosquitoes or ingestion of virus-infected mice
| Route of Exposure | Animal | WNV virus titer (log10 PFU/mL serum) at days postexposure | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 0.5 | 1.0 | 1.5 | 2.0 | 2.5 | 3.0 | 3.5 | 4.0 | 4.5 | 5.0 | 5.5 | 6.0 | 6.5 | 7.0 | 7.5 | 8.0 | 8.5 | 9.0 | ||
| Mosquito | Dog 1 | <1 | 1.6 | <1 | <1 | <1 | 1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | -a | - | - | - |
| Mosquito | Dog 2 | <1 | <1 | 2 | 2 | <1 | 2.2 | 2 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Mosquito | Dog 3 | <1 | <1 | <1 | <1 | <1 | 1 | 1.6 | 1.6 | 1 | 1 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Mosquito | Dog 4 | <1 | <1 | 1.6 | 1.6 | <1 | 1.6 | 1.6 | 1.6 | 1 | 1 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Mosquito | Cat 1 | <1 | 1.6 | 2.3 | 2.9 | 2.4 | 2.8 | 2.7 | 3.2 | 2 | 2 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Mosquito | Cat 2 | <1 | <1 | 2.1 | 2.3 | 2.4 | 2.7 | 2.8 | 3.0 | 2.6 | 1 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Mosquito | Cat 3 | <1 | <1 | <1 | 1 | 1.6 | 1.9 | 2.0 | 2.8 | 3.4 | 3.0 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Mosquito | Cat 4 | <1 | <1 | 1 | 2.5 | 3.2 | 3.2 | 4.0 | 3.2 | 3.0 | 1 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Oral | Cat 14 | <1 | - | 1 | 3.2 | 2.9 | 3.2 | 3.4 | 3.7 | 3.6 | 3.2 | <1 | <1 | <1 | <1 | <1 | - | - | - | - |
| Oral | Cat 16 | <1 | - | 2 | 2.7 | 2.8 | 3.4 | 3.6 | 3.9 | 3.6 | 2.7 | <1 | 1 | <1 | <1 | <1 | - | - | - | - |
| Oral | Cat 17 | - | <1 | <1 | <1 | <1 | <1 | <1 | <1 | 1.8 | 1.0 | 1.6 | 2.1 | 2.5 | 2.3 | 1.8 | 1.0 | 1.3 | <1 | <1 |
| Oral | Cat 18 | <1 | <1 | <1 | <1 | <1 | 1.8 | 1.3 | 1.5 | 1.0 | 1.6 | 2.2 | 1.5 | 1.3 | <1 | <1 | <1 | <1 | <1 | <1 |
a-, Not done.
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