Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 10, Number 1—January 2004


Respiratory and Urinary Tract Infections, Arthritis, and Asthma Associated with HTLV-I and HTLV-II Infection

Edward L. Murphy*, Baoguang Wang†, Ronald A. Sacher‡, Joy Fridey§, James W. Smith¶, Catharie C. Nass#, Bruce Newman**, Helen E. Ownby**, George Garratty††, Sheila T. Hutching††, and George B. Schreiber†
Author affiliations: *University of California San Francisco, California, USA; †Westat, Rockville, Maryland, USA; ‡Hoxworth Blood Center, Cincinnati, Ohio, USA; §Blood Bank of San Bernardino and Riverside Counties, San Bernardino, California, USA; ¶Oklahoma Blood Institute, Oklahoma City, Oklahoma, USA; #American Red Cross Blood Services Chesapeake and Potomac, Baltimore, Maryland, USA; **American Red Cross Blood Services Southeastern Michigan, Detroit, Michigan, USA; ††American Red Cross Blood Services Southern California, Los Angeles, California, USA

Main Article

Table 3

Incidence density (ID)a and standard deviation (SD) of medically diagnosed infectious diseases, and selected crude and adjusted rate ratios (RR), among human T-lymphotropic virus (HTLV)-I– and HTLV-II–infected participants and HTLV-seronegative participants, visits 2 and 3

Diagnosis HTLV seronegative 
(N = 799) HTLV-I (N = 152) HTLV-II (N = 387)
ID (SD) ID (SD) RRb Adj. RR (95% CI)c ID (SD) RRb Adj. RR (95% CI)c
Pneumonia 0.08 (0.37) 0.11 (0.47) 1.49 1.33 (0.66 to 2.66) 0.21 (0.96) 2.82 2.65 (1.67 to 4.21)
Acute Bronchitis 0.59 (1.78) 0.82 (2.25) 1.38 1.33 (0.84 to 2.12) 1.10 (2.75) 1.83 1.53 (1.10 to 2.14)
Bladder or Kidney infection 0.63 (2.04) 1.75 (4.61) 2.73 2.32 (1.50 to 3.59) 1.25 (3.48) 1.94 1.94 (1.40 to 2.68)

aDefined as the mean of the total number of infectious disease diagnoses divided by the number of participants (with or without the infection) in each group at baseline. The period of observation was 4.4 years (HTLV-I), 4.3 years (HTLV-II), and 4.4 years (HTLV seronegative), and each participant may have multiple diagnoses of each condition.bUnadjusted.
cAdjusted. Adjusted models included age, gender, race/ethnicity and duration of follow-up for all infections, and injection drug use (for pneumonia), smoking (for acute bronchitis), and community versus autologous blood donation (for bladder/kidney infection).

Main Article