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Volume 10, Number 1—January 2004


Severe Acute Respiratory Syndrome–associated Coronavirus in Lung Tissue

Tony Mazzulli*†‡, Gabriella A. Farcas‡§, Susan M. Poutanen*†‡, Barbara M. Willey*†, Donald E. Low*†‡, Jagdish Butany†‡¶, Sylvia L. Asa†‡¶, and Kevin C. Kain‡§1Comments to Author 
Author affiliations: *Mount Sinai Hospital, Toronto, Ontario, Canada; †Toronto Medical Laboratories, Toronto Ontario, Canada; ‡University of Toronto, Toronto, Ontario, Canada; §Toronto General Hospital, Toronto, Ontario, Canada; ¶University Health Network, Toronto, Ontario, Canada

Main Article

Table 2

Univariate analysis of predictors of high viral loads in postmortem lung tissue

Predictor Viral load >106 copies/g lung tissue Viral load <106 copies/g lung tissue Fisher exact test
Short duration of illness (<21 d) 5/5 0/6 p=0.002
Use of ribavirin 4/5 6/6 p=0.45
Use of steroids 1/5 5/6 p=0.08

Main Article

1Drs. Mazzulli and Farcas contributed equally to the manuscript. All authors jointly conceived and designed the study and wrote the report. Gabriella A. Farcas performed the majority of the reverse transcription-polymerase chain reaction assays.