Volume 10, Number 2—February 2004
THEME ISSUE
2004 SARS Edition
Laboratory Study
Detection of SARS Coronavirus in Patients with Suspected SARS
Kwok H. Chan*, Leo L.L.M. Poon†, V.C.C. Cheng*, Yi Guan†, I.F.N. Hung*, Joseph S.M. Peiris‡
, Loretta Y.C. Yam§, Wing H. Seto*, Kwok Y. Yuen†, and Joseph S. Malik Peiris†
, Loretta Y.C. Yam§, Wing H. Seto*, Kwok Y. Yuen†, and Joseph S. Malik Peiris†
Table 1
SARS-CoV RNA detection by RT-PCR in clinical specimensa
| Category | Patients tested | Patients positive (%) |
|---|---|---|
| Clinical | ||
| Clinical SARS (n = 590) | 537 | 322 (60.0) |
| Suspected SARS (n = 79) | 70 | 1 (1.4) |
| Non-SARS febrile respiratory illnesses (n = 379) | 341 | 2 (0.6) |
| Hospital controls | ||
| Cohort 1: fecal samples from non-SARS patients with diarrhea | 184 | 1 (0.5) |
| Community controls | ||
| Cohort 2: throat swabs from patients with nonrespiratory illness visiting community physicians. | 148 | 0 (0.0) |
aSARS, severe acute respiratory syndrome; SARS-CoV, severe acute respiratory syndrome coronavirus; RT-PCR, reverse transcriptase–polymerase chain reaction.
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