Volume 10, Number 3—March 2004
Dispatch
Endemic Carbapenem-resistant Pseudomonas aeruginosa with Acquired Metallo-β-lactamase Determinants in European Hospital
Cristina Lagatolla*
, Enrico A. Tonin*, Carlo Monti-Bragadin*, Lucilla Dolzani*, Francesca Gombac*, Claudia Bearzi*, Elisabetta Edalucci*, Fabrizia Gionechetti*, and Gian Maria Rossolini†
, Enrico A. Tonin*, Carlo Monti-Bragadin*, Lucilla Dolzani*, Francesca Gombac*, Claudia Bearzi*, Elisabetta Edalucci*, Fabrizia Gionechetti*, and Gian Maria Rossolini†
Table 1
Genetic relatedness, presence of MBL determinants, and distribution of the 89 imipenem-resistant Pseudomonas aeruginosa isolatesa
| No. of isolates | RAPD–AFLP genotypesb | blaVIM allele | Hospital wards (patients) | Long-term care facilities (patients) | Outpatients | |
|---|---|---|---|---|---|---|
| blaVIM-positive |
||||||
| 53 |
A |
blaVIM-1-like |
15 (43) |
3 (4) |
6 |
|
| 8 |
B |
blaVIM-2-like |
4c (8) |
- |
- |
|
| 1 |
C |
blaVIM-2-like |
1d (1) |
- |
- |
|
| 1 |
D |
blaVIM-2-like |
- |
1 (1) |
- |
|
| 1 |
E |
blaVIM-1-like |
- |
- |
1 |
|
| blaVIM-negative |
||||||
| 5 |
A |
None |
2 (3) |
- |
2 |
|
| 1 |
B |
None |
1 (1) |
- |
- |
|
| 19 | F-G-H-I-J-Ke | None | 8 (16) | 1 (1) | 2 | |
a MBL, metallo-β-lactamase.
bRAPD–AFLP, Random Amplification of Polymorphic DNA–Amplified Fragment Length Polymorphism. Results obtained with the two genotyping techniques were always consistent with each other.
cIn these wards isolates of cluster A were also detected.
dIn this ward isolates of clusters A and B were also detected.
eGenotypes F to K included a number of isolates ranging from 1 to 7.
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