Volume 10, Number 5—May 2004
Research
Virulence Factors for Hemolytic Uremic Syndrome, Denmark1
Steen Ethelberg*
, Katharina E. P. Olsen*, Flemming Scheutz*†, Charlotte Jensen*, Peter Schiellerup*, Jørgen Engberg*, Andreas Munk Petersen*, Bente Olesen*, Peter Gerner-Smidt*, and Kåre Mølbak*
, Katharina E. P. Olsen*, Flemming Scheutz*†, Charlotte Jensen*, Peter Schiellerup*, Jørgen Engberg*, Andreas Munk Petersen*, Bente Olesen*, Peter Gerner-Smidt*, and Kåre Mølbak*
Table 3
Risk factors for HUS among 343 STEC patients, Denmark, 1997–2003a
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Determinant |
No. of patients |
No. (%) with HUS |
OR |
95% CI |
OR |
95% CI |
| eae |
||||||
| Negative |
111 |
0 |
1 |
|||
| Positive |
232 |
21 (9.1) |
NDb |
NI |
||
| stx2 |
||||||
| Negative |
159 |
1 (0.6) |
1 |
1 |
||
| Positive |
184 |
20 (10.9) |
19.3 |
2.6 to 145 |
18.9 |
2.4 to 146 |
| Age |
||||||
| >8 y |
178 |
3 (1.7) |
1 |
1 |
||
| <7 y |
165 |
18 (10.9) |
7.5 |
2.2 to 26.0 |
11.4 |
3.2 to 41.3 |
| Bloody diarrhea |
||||||
| No |
218 |
6 (2.8) |
1 |
1 |
||
| Yes |
125 |
15 (12.0) |
4.8 |
1.8 to 12.8 |
4.5 |
1.6 to 12.7 |
| O157 |
||||||
| No |
262 |
10 (3.8) |
1 |
|||
| Yes |
81 |
11 (13.6) |
4.0 |
1.6 to 9.7 |
NS |
|
| O111 |
||||||
| No |
337 |
19 (5.6) |
1 |
|||
| Yes | 6 | 2 (33.3) | 8.4 | 1.4 to 48.6 | NS | |
aSTEC, Shiga toxin–producing Escherichia coli; HUS, hemolytic uremic syndrome; OR, odds ratio; CI, confidence intervals; NI, not included (test not appropriate); ND, not defined; NS, not statistically significant.
bp < 0.0002, Fisher exact test.
1Presented in part at the VTEC2003, 5th International Symposium on “Shiga Toxin (Verocytotoxin) Producing Escherichia coli Infections,” Edinburgh, Scotland, June 2003 (abstract O-6).
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