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Volume 11, Number 1—January 2005
Dispatch

Invasive Group A Streptococcal Infection in High School Football Players, New York City, 2003

Susan E. Manning*†Comments to Author , Elsie Lee†, Maribeth Bambino‡, Joel Ackelsberg†, Don Weiss†, Chiminyan Sathyakumar†, John Kornblum†, Oxiris Barbot†, Dwight Johnson§, Edward L. Kaplan§, and Marcelle Layton†
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †New York City Department of Health and Mental Hygiene, New York, New York, USA; ‡Montefiore Medical Center, Department of Infectious Diseases, Bronx, New York, USA; §World Health Organization Collaborating Center for Reference and Research on Streptococci, Minneapolis, Minnesota, USA

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Table

Characterization of group A Streptococcus isolates from high-school varsity and junior varsity football players, New York City, 2003

Specimen origin Site Antimicrobial susceptibility* PFGE† M/OF†/emm type
Varsity player
  A‡ Blood Susceptible to all antimicrobial agents tested 82
  B Throat Resistant to erythromycin, susceptible to all others Unrelated§ 75
  C Throat Susceptible to all antimicrobial agents tested Unrelated 6
  D Throat Intermediate to tetracycline, susceptible to all others Indistinguishable 82
Junior varsity player
  E Throat Susceptible to all antimicrobial agents tested Unrelated 89
  F Throat Susceptible to all antimicrobial agents tested Unrelated 44/61
  G Throat Susceptible to all antimicrobial agents tested Unrelated 28
  H Throat Susceptible to all antimicrobial agents tested Unrelated 118

*Antimicrobial agents tested: chloramphenicol, clindamycin, erythromycin, penicillin G, tetracycline, vancomycin.
†Entries represent putative genetic relatedness to the case-patient no. 1 strain A based on SmaI and SfiI DNA restriction patterns by using categories as defined by Tenover et al. (5). The results obtained with Sfi I correlated completely with the results obtained with SmaI; PFGE, pulse-field gel electrophoresis; OF, opacity-factor.
‡Case-patient #1.
§Specimen B was nontypable with SmaI but was typable with SfiI.

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References
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