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Volume 11, Number 1—January 2005

SARS Clinical Features, United States, 2003

Padmini Srikantiah*1, Myrna D. Charles*, Sarah Reagan*, Thomas A. Clark*, Mathias W.R. Pletz*, Priti R. Patel*, Robert M. Hoekstra*, Jairam Lingappa*2, John A. Jernigan*, Marc Fischer*Comments to Author , and for the CDC SARS Clinical Investigation Team
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 3

Univariate analysis for distinguishing clinical features of SARS-CoV–positive cases from SARS-CoV–negative controls, United States, 2003*

Clinical feature SARS-CoV–positive cases (N = 8), n (%) SARS-CoV–negative controls (N = 65), n (%) OR (95% CI) p value
Dyspnea 8 (100) 32 (49) 10.9 (1.6, ∞) 0.01
Hypoxia 5 (63) 9 (14) 9.9 (1.6, 75.0) 0.01
Rales 5 (63) 15 (23) 5.4 (0.9, 38.9) 0.06
Sore throat 1 (13) 39 (60) 0.1 (0.0, 0.8) 0.03
Vomiting 5 (63) 3 (5) 30.5 (4.0, 315.4) < 0.01
Diarrhea 6 (75) 18 (28) 7.6 (1.2, 83.6) 0.02
Radiographic evidence of infiltrates at first evaluation 6 (75) 12† (23) 10.0 (1.8, 56.2) < 0.01
Lymphopenia 7 (88) 24‡ (53) 6.0 (0.7, 288.9) > 0.10

*SARS-CoV, severe acute respiratory syndrome–associated coronavirus; OR, odds ratio; CI, confidence interval.
†Among 52 controls who had chest radiograph performed.
‡Among 45 controls who had complete blood counts performed.

Main Article

1Dr. Srikantiah is currently a fellow in the Division of Infectious Diseases at the University of California San Francisco.

2Dr. Lingappa is an assistant professor in the Department of Medicine at the University of Washington.

3The CDC SARS Clinical Investigation Team included Akinyi Adija, Bernadette Albanese, Cindy Allard, Felicia Alvarez, Fermin Arguello, Gregory Armstrong, Christine Barton, Geoff Beckett, William Bellini, Megan Davies, Paul Drummond, Dean Erdman, Leigh Farrington, Dara Friedman, Ken Gershman, Jayne Griffith, Kevin Griffith, Heath Harmon, Rita Helfand, Jo Hoffman, Gregory Huhn, Daniel Jernigan, Geraldine Johnson, Paul Kitsutani, Thomas Ksiazek, Ashley LaMonte, Bhrett Lash, Kathryn Lofy, Ruth Lynfield, Joseph Malone, Bela Matyas, Clifford McDonald, Marty Monroe, Steven Monroe, Pat Mshar, Maureen Murphy, Michelle Packard, Neil Pascoe, Michael Phillips, James Rankin, Chesley Richards, Corey Robertson, Peggy Robinson-Dixon, Marc Romney, Maria Pia Sanchez, David Shay, Chad Smelser, David Stephens, Shelley Stonecipher, Tina Tan, Sharon Thompson, J. Todd Weber, and Cindy Weinbaum.

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