Volume 11, Number 12—December 2005
Research
Viral Load Distribution in SARS Outbreak
Chung-Ming Chu*, Vincent C.C. Cheng†, Ivan F.N. Hung†, Kin-Sang Chan*, Bone S.F. Tang†, Thomas H.F. Tsang‡, Kwok-Hung Chan†, and Kwok-Yung Yuen†
Table
Demographic factors on admission of patients living in E block and non-E block of Amoy Gardens, Hong Kong*
| Factor | E block patients (n = 53) | Non-E block patients (n = 26) | p value |
|---|---|---|---|
| Age, y, mean (SD) | 40.6 (11.9) | 37.1 (10.6) | 0.21†|
| Male:female ratio | 25:28 | 13:13 | 0.81‡ |
| Duration of symptoms to admission (days), mean (SD) | 2.4 (1.2) | 2.5 (1.2) | 0.72†|
| Coexisting conditions including chronic hepatitis B, no. (%) | 11 (19.6) | 8 (30.8) | 0.33‡ |
| Chronic hepatitis B infection, no. (%) | 5 (9.4) | 5 (19.2) | 0.22‡ |
| Abnormal chest radiograph results, no. (%) | 38 (71.7) | 21 (80.8) | 0.38‡ |
| Multilobar involvement on initial chest radiograph, no. (%) | 13 (24.5) | 5 (19.2) | 0.60‡ |
| Day of collection of nasopharyngeal specimens after onset of symptoms, mean (SD) | 3.2 (1.2) | 3.3 (1.8) | 0.74†|
| Quantitative RT-PCR result of nasopharyngeal specimens (log10 copies/mL), median (IQR) | 5.09 (3.50–6.59) | 0 (0–3.57) | 0.008§ |
| Hemoglobin (g/dL), mean (SD) | 13.3 (1.7) | 13.8 (1.4) | 0.24†|
| Neutrophil count (× 109/L), mean (SD) | 5.2 (2.0) | 5.3 (2.0) | 0.77†|
| Lymphocyte count (× 109/L), mean (SD) | 0.92 (0.6) | 0.86 (0.4) | 0.65†|
| Sodium (mmol/L), mean (SD) | 138 (3) | 138 (3) | 0.91†|
| Potassium (mmol/L), mean (SD) | 3.9 (3.6) | 3.9 (3.0) | 0.31†|
| Urea (mmol/L), mean (SD) | 4.4 (1.4) | 4.1 (1.0) | 0.34†|
| Creatinine (μmol/L), mean (SD) | 88 (16) | 85 (12) | 0.35†|
| Alanine aminotransferase (IU/L), mean (SD) | 41 (49) | 31 (19) | 0.31†|
| Albumin (g/L), mean (SD) | 40 (3) | 40 (3) | 0.85†|
| Creatinine kinase (IU/L), mean (SD) | 197 (222) | 190 (186) | 0.89†|
| Lactate dehydrogenase (IU/L), mean (SD) | 437 (190) | 398 (107) | 0.47†|
*SD, standard deviation; IQR, interquartile ratio; RT-PCR, reverse transcription–polymerase chain reaction.
†By Student t test.
‡By chi-square test.
§By Mann-Whitney U test.
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