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Volume 11, Number 2—February 2005
Research

Pneumocystis jirovecii in General Population

Francisco J. Medrano*Comments to Author , Marco Montes-Cano*, Manuel Conde*, Carmen de la Horra*, Nieves Respaldiza*, Antonia Gasch*, Maria J. Perez-Lozano*, Jose M. Varela*, and Enrique J. Calderon*
Author affiliations: *Virgen del Rocío University Hospital, Seville, Spain

Main Article

Table

Epidemiologic, biologic, and microbiologic features of healthy Pneumocystis carriers*

Participant (age [y], sex)† Profession Alcohol intake >40 g/day Smoking habit Total lymphocyte count (cells/μL) CD4+ cell count (cells/μL) mtLSU-rRNA genotype (nucleotide position: identity) DHPS genotype (codon position: identity) by PCR-RFLP assay PCR result at month
6 of 
follow-up
1 (28, F) Administrative No No 2,327 653 3 (85:T/248:C) 1 (55:Thr/57:Pro) +
2 (42, F) Administrative No No 2,455 1,168 1 (85:C/248:C) 1 (55:Thr/57:Pro)
3 (43, F) Administrative No No NA NA 4 (85:C/248:T) Not amplified
4 (40, M) Administrative Yes No 1,528 520 3 (85:T/248:C) Not amplified
5 (41, F) New resident No No NA NA 2 (85:A/248:C) 1 (55:Thr/57:Pro) NA
6 (27, F) New resident No No 1,354 550 2 (85:A/248:C) 1 (55:Thr/57:Pro)
7 (32, F) New resident No No 2,300 604 1 (85:C/248:C) 1 (55:Thr/57:Pro)
8 (40, M) University staff Yes Yes 1,730 924 2 (85:A/248:C) 1 (55:Thr/57:Pro) +
9 (26, M) University staff Yes Yes 3,602 924 2 (85:A/248:C) 1 (55:Thr/57:Pro)
10 (42, M) University staff No No 1,518 432 1 (85:C/248:C) Not amplified

*mtLSU-rRNA, mitochondrial large subunit ribosomal RNA; DHPS, dihydropteroate synthase; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; F, female; M, male; +, positive result; –, negative result; NA, not available.
†Chest radiograph results were normal for all participants, except participant 5, for whom results were not available, and participant 9, who showed an apical cystic bullae.

Main Article

Page created: April 27, 2011
Page updated: April 27, 2011
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