Volume 11, Number 6—June 2005
Research
Community-associated Methicillin-resistant Staphylococcus aureus, Canada
Table 2
Antimicrobial agent | Clonal group A (n = 55) |
Clonal group B (n = 126) |
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---|---|---|---|---|---|---|---|---|
MIC50 (mg/L) | MIC90 (mg/L) | % resistant | Range | MIC50 (mg/L) | MIC90 (mg/L) | % resistant | Range | |
Oxacillin | 16 | 32 | 100 | 4–64 | 16 | 32 | 100 | 4–64 |
Cefazolin | 32 | 32 | 75 | 4–32 | 16 | 32 | 31 | 2–32 |
Ciprofloxacin | 32 | ≥32 | 86 | 0.25–≥32 | 0.25 | 0.25 | 0 | 0.25–0.5 |
Clindamycin | <0.25 | ≥8 | 11 | <0.25–≥8 | <0.25 | <0.25 | 1.6 | <0.25–≥8 |
Erythromycin | >8 | ≥8 | 87 | <0.25–≥8 | <0.25 | ≥8 | 40 | <0.25–≥8 |
Gentamicin | >16 | ≥16 | 64 | <0.5–≥16 | <0.5 | <0.5 | 0 | <0.5 |
Rifampin | <0.25 | <0.25 | 3.6 | <0.25–≥4 | <0.25 | <0.25 | 0 | <0.25 |
Tetracycline | 16 | ≥16 | 55 | <2–≥16 | <2 | <2 | 0 | <2 |
Trimethoprim/sulfamethoxazole | <0.25 | 0.5 | 5.5 | <0.25 | <0.25 | <0.25 | 0 | <0.25 |
Vancomycin | 1.0 | 1.0 | 0 | 1.0 | 1.0 | 1.0 | 0 | 0.5-1.0 |
Linezolid | 4.0 | 4.0 | 0 | 4.0 | 2.0 | 4.0 | 0 | 1.0-4.0 |
Mupirocin | ≥128 | ≥128 | 58 | ≥128 | ≥128 | ≥128 | 55.6 | <0.25–≥128 |
Fusidic acid | ≥8 | ≥8 | 100 | ≥8.0 | 0.12 | 0.25 | 0 | 0.12–0.25 |
1Members of the Saskatchewan CA-MRSA Study Group: N. Antonishyn, Provincial Laboratory Saskatchewan Health, Regina, SK; T. Du, National Microbiology Laboratory, Winnipeg, MB; J. Embil, University of Manitoba, Winnipeg, MB; A. Graessli, University of Manitoba, Winnipeg, MB; J. Irvine, Keewatin Yatthe & Mamaweetan Churchill Regional Health Authority, La Ronge, SK; M. Khan, Kelsey Trail Health Region, Melfort, SK; S. Martin, Kelsey Trail Health Region, Nipawin, SK; R. McDonald, Provincial Laboratory Saskatchewan Health, Regina, SK; M. Nsungu, Northern Intertribal Health Authority, Prince Albert, SK; S. Paton, Public Health Agency of Canada, Ottawa, ON; C. Celin, National Microbiology Laboratory, Winnipeg, MB; D. Spreitzer, National Microbiology Laboratory, Winnipeg, MB; D. Stockdale, Keewatin Yatthe & Mamaweetan Churchill Regional Health Authority, La Ronge, SK.