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Volume 12, Number 4—April 2006
Letter

Lack of Transmission of Vaccinia Virus

James H. Stark*, Sharon E. Frey†, Paul S. Blum*, and Thomas P. Monath*Comments to Author 
Author affiliations: *Acambis Inc., Cambridge, Massachusetts, USA; †St. Louis University School of Medicine, St. Louis, Missouri, USA

Main Article

Table

Sampling outcomes of 43 study participants who received 1 of 3 smallpox vaccines

Variable All participants (N = 43) Vaccine group
ACAM1000 (n = 14) ACAM2000 (n = 15) Dryvax (n = 14)
Mean ± SD titer from lesion*†‡
Day 7 3.84 ± 0.98 3.77 ± 1.15 3.85 ± 1.06 3.91 ± 0.74
Day 10 3.75 ± 0.89 3.62 ± 0.54 3.58 ± 1.21 4.07 ± 0.74
Day 15 4.19 ± 1.40 4.08 ± 1.24 3.67 ± 1.57 4.86 ± 1.18
Mean ± SD titer from dressing§
Day 7 0.63 ± 0.85 0.9 ± 1.50 0 0
Day 10 0 0 0 0
Day 15 0 0 0 0

*Viral shedding results reported as <X were converted to X/2 before calculating.
†Titers are reported as log10 PFU/mL.
‡There were no significant differences among the groups (p>0.05).
§Limit of detection was 1.0 log10 PFU/mL.

Main Article

Page created: January 24, 2012
Page updated: January 24, 2012
Page reviewed: January 24, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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