Volume 12, Number 7—July 2006
Dispatch
Transmission of New Bovine Prion to Mice
Thierry G.M. Baron*
, Anne-Gaëlle Biacabe*, Anna Bencsik*, and Jan P.M. Langeveld†
, Anne-Gaëlle Biacabe*, Anna Bencsik*, and Jan P.M. Langeveld†
Table
Cattle sources of transmissible spongiform encephalopathy (TSE) used for experimental infections of C57BL/6 mice and transmission results*
| Cattle TSE isolate | Age, y | Breed | Molecular type | Survival periods (d) in C57BL/6 mice (mean ± SD) | Western blot results† |
|---|---|---|---|---|---|
| 1 | 8 | Charolais | H | 702 ± 117 | 8/9 |
| 2 | 12 | Crossbreed | H | 652 ± 85 | 10/10 |
| 3 | 4 | Prim'Holstein | Typical | 511 ± 89 | 8/9 |
*SD, standard deviation.
†No. mice positive for disease-associated prion protein/no. mice analyzed.
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