Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 12, Number 9—September 2006
Research

Multidrug-resistant Tuberculosis Management in Resource-limited Settings

Eva Nathanson*Comments to Author , Catharina Lambregts-van Weezenbeek†, Michael Rich‡, Rajesh Gupta*, Jaime Bayona‡§, Kai Blöndal†, José A. Caminero¶, J. Peter Cegielski#, Manfred Danilovits**, Marcos A. Espinal*, Vahur Hollo††, Ernesto Jaramillo*, Vaira Leimane‡‡, Carole D. Mitnick§§, Joia S. Mukherjee§§, Paul Nunn*, Alexander Pasechnikov‡¶¶, Thelma E. Tupasi##, Charles Wells#, and Mario C. Raviglione*
Author affiliations: *World Health Organization, Geneva, Switzerland; †KNCV Tuberculosis Foundation, The Hague, the Netherlands; ‡Partners In Health, Boston, Massachusetts, USA; §Socios En Salud, Lima, Peru; ¶International Union Against Tuberculosis and Lung Disease, Paris, France; #Centers for Disease Control and Prevention, Atlanta, Georgia, USA; **Tartu University Clinics, Tartu, Estonia; ††National TB Programme, Tallinn, Estonia; ‡‡State Centre of Tuberculosis and Lung Diseases of Latvia, Riga, Latvia; §§Harvard Medical School, Boston, Massachusetts, USA; ¶¶MDR-TB Project in Tomsk Oblast, Tomsk, Russian Federation; ##Makati Medical Center, Makati, the Philippines

Main Article

Table 3

Frequency of drugs used in multidrug-resistant tuberculosis control program treatment regimens

Drug Estonia, n (%) Latvia, n (%) Lima, n (%) Manila, n (%) Tomsk, n (%) Total, n (%)
Ethambutol 44 (95.7) 117 (47.8) 102 (20.1) 43 (41.0) 28 (19.6) 334 (31.9)
Pyrazinamide 1 (2.2) 99 (40.4) 146 (28.7) 88 (83.8) 84 (58.7) 418 (39.9)
Streptomycin 1 (2.2) 9 (3.7) 104 (20.5) 51 (48.6) 0 165 (15.8)
Capreomycin 11 (23.9) 115 (46.9) 199 (39.2) 23 (21.9) 94 (65.7) 442 (42.2)
Cycloserine 45 (97.8) 189 (77.1) 316 (62.2) 100 (95.2) 142 (99.3) 792 (75.6)
Ciprofloxacin 0 0 257 (50.6) 18 (17.1) 0 275 (26.3)
Clofazimine 0 0 13 (2.6) 0 0 13 (1.2)
Kanamycin 7 (15.2) 129 (52.7) 167 (32.9) 91 (86.7) 47 (32.9) 441 (42.1)
Levofloxacin 1 (2.2) 0 0 30 (28.6) 0 31 (3.0)
Ofloxacin 35 (76.1) 242 (98.8) 44 (8.7) 87 (82.9) 142 (99.3) 550 (52.5)
p-Aminosalicylic acid 26 (56.5) 71 (29.0) 323 (63.6) 98 (93.3) 118 (82.5) 636 (60.7)
Prothionamide or ethionamide 38 (82.6) 154 (62.9) 244 (48.0) 104 (99.0) 94 (65.7) 634 (60.6)
Augmentin 4 (8.7) 7 (2.9) 325 (64.0) 0 2 (1.4) 338 (32.3)
Clarithromycin 4 (8.7) 1 (0.4) 67 (13.2) 46 (43.8) 3 (2.1) 121 (11.6)
Sparfloxacin 0 0 0 14 (13.3) 0 14 (1.3)
Thiacetazone 0 164 (66.9) 0 0 0 164 (15.7)

Main Article

Page created: November 17, 2011
Page updated: November 17, 2011
Page reviewed: November 17, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external