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Volume 13, Number 1—January 2007

Research

Panmicrobial Oligonucleotide Array for Diagnosis of Infectious Diseases

Gustavo Palacios*1, Phenix-Lan Quan*1, Omar J. Jabado*, Sean Conlan*, David L. Hirschberg†, Yang Liu‡, Junhui Zhai*, Neil Renwick*, Jeffrey Hui*, Hedi Hegyi*§, Allen Grolla¶, James E. Strong¶, Jonathan S. Towner#, Thomas W. Geisbert**, Peter B. Jahrling††, Cornelia Büchen-Osmond*, Heinz Ellerbrok‡‡, Maria Paz Sanchez-Seco§§, Yves Lussier‡, Pierre Formenty¶¶, Stuart T. Nichol#, Heinz Feldmann¶##, Thomas Briese*, and W. Ian Lipkin*Comments to Author 

Author affiliations: *Columbia University, New York, New York, USA; †Stanford University, Stanford, California, USA; ‡University of Chicago, Chicago, Illinois, USA; §Institute of Enzymology, Budapest, Hungary; ¶Public Health Agency of Canada, Winnipeg, Manitoba, Canada; #Centers for Disease Control and Prevention, Atlanta, Georgia, USA; **US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA; ††National Institutes of Health Integrated Research Facility, Fort Detrick, Frederick, Maryland, USA; ‡‡Robert Koch Institut, Berlin, Germany; §§Instituto de Salud Carlos III, Madrid, Spain; ¶¶World Health Organization, Geneva, Switzerland; ##University of Manitoba, Winnipeg, Manitoba, Canada;

Main Article

Table 3

Clinical samples used to test GreeneChip performance

PathogenGenusSample
SARS* coronavirusCoronavirusLung
Human respiratory syncytial virus APneumovirusNasopharyngeal
Human enterovirus A (CAV10)EnterovirusNasopharyngeal
Lake Victoria marburgvirusMarburgvirusBlood
Influenza A virus (H1N1)OrthomyxovirusNasopharyngeal
Klebsiella pneumoniae†KlebsiellaUrine
Escherichia coli†EscherichiaUrine
Mycobacterium tuberculosis‡MycobacteriumLung
Mycobacterium tuberculosis‡MycobacteriumEndometrial biopsy
Lactobacillus sp.§LactobacillusUrine

*SARS, severe acute respiratory syndrome.
†Detected on the array as a gammaproteobacterium.
‡Detected on the array as a mycobacterium.
§Detected on the array as a lactobacillus.

Main Article

1These authors contributed equally to this study.

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