Volume 13, Number 10—October 2007
Research
Rapid Increase of Genetically Diverse Methicillin-Resistant Staphylococcus aureus, Copenhagen, Denmark
Table 1
Demographics, infection types, and distribution of MRSA types in 143 cases of MRSA*
Community onset, community risk | Community onset, no risk | Hospital acquired in Denmark | Community onset, healthcare associated | Imported | |
---|---|---|---|---|---|
No. cases | 30 | 35 | 37 | 36 | |
Male, % | 67 | 46 | 57 | 42 | |
Median age, y (range) | 27 (1–74) | 32 (0–90) | 80 (28–94) | 82 (6–95) | |
Carrier, no. |
8 |
1 |
2 |
2 |
4† |
Type of infection, no. | |||||
SSTI | 22 | 29 | 17 | 23 | |
Blood | 0 | 0 | 2 | 2 | |
Deep-seated abscess, no. | 0 | 1 | 5 | 3 | |
UTI | 0 | 4 | 8 | 5 | |
LRTI |
0 |
0 |
3 |
1 |
1† |
Four most common CCs (87% of all isolates) | |||||
CC 8, % | 23 | 34 | 81 | 69 | |
t008, no. | 3 | 7 | 0 | 2 | |
t024, no. | 3 | 5 | 28 | 20 | |
CC 80, % | 20 | 34 | 3 | 0 | |
CC 30, % | 50 | 6 | 0 | 0 | |
CC 5, % | 3 | 11 | 5 | 8 | |
Other MLST types,% | 4 | 15 | 11 | 23 | |
PVL positive, % | 83 | 80 | 8 | 17 | |
SCCmec IV, % | 93 | 89 | 89 | 81 |
*MRSA, methicillin-resistant Staphylococcus aureus; SSTI, skin and soft tissue infection; UTI, urinary tract infection; LRTI, lower respiratory tract infection; CC, clonal complex; MLST, multilocus sequence typing; PVL, Panton-Valentine leukocidin; SCC, staphylococcal chromosome cassette.
†A t037/ST239-III was imported from Greece, where this MRSA is common (20); ST239 is closely related to ST8 and is the well-known pandemic Brazilian/Hungarian clone (21); t041/ST111 was imported from an Italian hospital; t003/ST225-II (New York clone) was imported from Germany; t354/ST22-IV, a variant of EMRSA15, was imported from Lanzarote (Spain); and t067/ST125-I was imported from Spain.
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