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Volume 13, Number 12—December 2007
Research

Susceptibility of Canada Geese (Branta canadensis) to Highly Pathogenic Avian Influenza Virus (H5N1)

John Pasick*Comments to Author , Yohannes Berhane*, Carissa Embury-Hyatt*, John Copps*, Helen Kehler*, Katherine Handel*, Shawn Babiuk*, Kathleen Hooper-McGrevy*, Yan Li†, Quynh Mai Le‡, and Song Lien Phuong§
Author affiliations: *Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada; †Public Health Agency of Canada, Winnipeg, Manitoba, Canada; ‡National Institute of Hygiene and Epidemiology, Hanoi, Vietnam; §National Center for Veterinary Diagnosis, Hanoi, Vietnam;

Main Article

Figure 2

Immunohistochemical (IHC) staining for influenza virus nucleoprotein in tissues of naïve juvenile Canada geese after challenge with influenza virus (H5N1). A) Pancreas. Large areas of necrosis are surrounded by pancreatic acinar cells with strong positive intranuclear and intracytoplasmic immunolabeling. B) Heart. Positive intranuclear and intracytoplasmic immunolabeling of myocytes. C) Proventriculus. Strong positive immunolabeling of compound tubular gland epithelium. D) Splenic arteriole. Positive IHC staining of vascular smooth muscle cells.

Figure 2. Immunohistochemical (IHC) staining for influenza virus nucleoprotein in tissues of naïve juvenile Canada geese after challenge with influenza virus (H5N1). A) Pancreas. Large areas of necrosis are surrounded by pancreatic acinar cells with strong positive intranuclear and intracytoplasmic immunolabeling. B) Heart. Positive intranuclear and intracytoplasmic immunolabeling of myocytes. C) Proventriculus. Strong positive immunolabeling of compound tubular gland epithelium. D) Splenic arteriole. Positive IHC staining of vascular smooth muscle cells.

Main Article

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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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