Volume 13, Number 8—August 2007
Dispatch
Possible Autochthonous Malaria from Marseille to Minneapolis
Table 2
Dhfr |
Dhps |
Pfcrt |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
51 | 16 | 108 | 164 | 59 | 613 | 540 | 581 | 436 | 437 | 76 | |||
Autochthonous 1† | – | GCA | AAC | ATA | TGT | GCC | AAA | GCG | TCT | GCT | ACA | ||
Autochthonous 2‡ | ATT | GCA | AAC | ATA | CGT | GCC | AAA | GCG | TCT | GGT | AAA | ||
3D7§ | AAT | GCA | AGC | ATA | TGT | GCC | AAA | GCG | TCT | GGT | AAA | ||
W2§ | ATT | GCA | AAC | ATA | CGT | TCC | AAA | GCG | TTT | GGT | ACA |
*Dhfr, dihydrofolate reductase gene; Dhps, dihydropteroate synthase; Pfcrt, P. falciparum chloroquine-resistance transporter. Underlines indicate positions that can be mutated.
†Patient 1, P. falciparum diagnosed in France.
‡Patient 2, P. falciparum diagnosed in the United States.
§Two parasite strains (3D7 and W2) were genotyped as a positive control; water was used as a negative control.
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