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Volume 14, Number 1—January 2008
Dispatch

Protochlamydia naegleriophila as Etiologic Agent of Pneumonia

Nicola Casson*, Rolf Michel†, Karl-Dieter Müller, John David Aubert*, and Gilbert Greub*Comments to Author 
Author affiliations: *University Hospital Center and University of Lausanne, Lausanne, Switzerland; †Central Institute of the Federal Armed Forces Medical Services, Koblenz, Germany; ‡Institut für Medizinische Mikrobiologie der Universität Essen, Essen, Germany;

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Table 1

Antibody titers and serologic differentiation index (SDI) obtained from reciprocal cross-reactions of mouse antiserum with different Chlamydia-like organisms, as determined by immunofluorescence* www.cdc.gov/EID/content/14/1/168-T1.htm

Strains Antigen titers (SDI)
Pr. naegleriophila Pr. amoebophila Simkania negevensis P. a. strain Seine Waddlia chondrophila Neoclamydia hartmannellae Criblamydia sequanensis R. crassificans
Pr. naegleriophila 4,096 (0) 256 (7) <4 (14) 512 (10) 4 (20) 16 (14) <4 (20) <4 (13)
Pr. amoebophila 32 (7) 256 (0) <32 (5) 1,024 (3) 64 (10) 32 (0) 128 (9) 64 (3)
S. negevensis 32 (14) 128 (5) 512 (0) 64 (12) 128 (12) <32 (12) 512 (8) 256 (3)
P. strain Seine 128 (10) 512 (3) 32 (12) 16,384 (0) 64 (19) 64 (12) <32 (19) <32 (12)
W. chondrophila 32 (20) 128 (10) 32 (12) <32 (19) 32,768 (0) <32 (18) 512 (13) 128 (10)
N. hartmannellae 32 (14) 128 (0) <32 (12) 128 (12) <32 (18) 2,048 (0) <32 (18) <32 (11)
C. sequanensis 32 (20) 128 (9) 128 (8) 64 (19) 256 (13) <32 (18) 32,768 (0) 128 (8)
R. crassificans 32 (13) 128 (3) 64 (3) 64 (12) 64 (10) <32 (11) 256 (8) 256 (0)

*Pr., Protochlamydia; P. a., Parachlamydia acanthamoebae; R., Rhabdochlamydia. Titers highlighted in gray, previously published in (9), are provided here because these data were used to calculate SDI between Pr. naegleriophila strain KNic and the other Chlamydia-related bacteria.

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References
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