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Volume 14, Number 11—November 2008
Dispatch

Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Alexander C. AichelburgComments to Author , Julia Walochnik, Ojan Assadian, Helmut Prosch, Andrea Steuer, Gedeon Perneczky, Govinda S. Visvesvara, Horst Aspöck, and Norbert Vetter
Author affiliations: Otto Wagner Hospital, Vienna, Austria (A.C. Aichelburg, A. Steuer, N. Vetter, H. Prosch); Medical University of Vienna, Vienna (J. Walochnik, O. Assadian, H. Aspöck); Krankenanstalt Rudolfstiftung, Vienna (G. Perneczky); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (G.S. Visvesvara);

Main Article

Table

Diagnosis of Acanthamoeba spp. and mycobacterial infection*

Organism, patient specimen Microscopy PCR Culture Immunostaining Serology
Acanthamoeba spp.
Cerebrospinal fluid Negative Positive Negative NA NA
Brain biopsy Negative Positive Negative Negative NA
Bronchial secretions Negative Positive Negative NA NA
Lung biopsy Negative Positive Negative Negative NA
Skin biopsy Negative Positive Negative NA NA
Blood
 NA
 NA
 NA
 NA
 Positive
Mycobacterium tuberculosis
Cerebrospinal fluid Positive Positive Positive NA NA
Brain operative specimen Positive Positive Negative NA NA
Sputum Negative Positive NA NA NA
Bronchial secretions Negative Positive Positive NA NA
Lung biopsy Negative Negative Negative NA NA
Blood NA Positive Negative NA NA

*NA, not available.

Main Article

Page created: July 16, 2010
Page updated: July 16, 2010
Page reviewed: July 16, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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