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Volume 14, Number 11—November 2008


Mixture for Controlling Insecticide-Resistant Malaria Vectors

Cédric Pennetier1Comments to Author , Carlo Costantini, Vincent Corbel, Séverine Licciardi, Roch K. Dabiré, Bruno Lapied, Fabrice Chandre, and Jean-Marc Hougard
Author affiliations: Institut de Recherche pour le Développement, Cotonou, Bénin (C. Pennetier, S. Licciardi, F. Chandre, J.-M. Hougard); Institut de Recherche pour le Développement , Bobo-Dioulasso, Burkina Faso (C. Costantini); Centre de Recherche Entomologique de Cotonou, Cotonou (C. Pennetier, S. Licciardi, F. Chandre, J.-M. Hougard); Institut de Recherche en Sciences de la Santé, Bobo-Dioulasso (C. Costantini, R.K. Dabiré); Institut de Recherche pour le Développement, Montpellier, France (V. Corbel); Université d’Angers, Angers, France (B. Lapied);

Main Article

Table 2

Regression parameters (standard errors) and median and 90% effective duration of effectiveness of antimalarial vector treatments*

Treatment a b ET50, d (95% CI) ET90, d
First trial
PM+DEET 2.814 (±0.737) –0.194 (±0.039) 14.5 (11.1–16.4) 3.2
PM+KBR 5.932 (±0.628) –0.337 (±0.032) 17.6 (16.8–18.2) 11.1
2.693 (±0.656)
–0.100 (±0.033)
26.8 (22.7–42.2)
Second trial
PM+DEET 2.907 (±0.520) –0.184 (±0.030) 15.8 (13.8–17.7) 3.9
PM+KBR 1.424 (±0.657) –0.090 (±0.036) 15.9 (5.4–22.7) –8.6
Kothrin 0.136 (±0.320) –0.030 (±0.019) 4.5 (0–13.9) –68.1

*First trial run in dry season (May and June); second trial run in rainy season (September and October). a, intercept; b, slope of curve; ET50 and ET90, median and 90%, respectively, effective time of the minimal adequate regression model fitted to the experimental hut data; CI, confidence interval; PM, pirimiphos methyl; DEET, diethyl-3-methylbenzamide; KBR, hydroxyethyl isobutyl piperidine carboxylate; Kothrin, 20% deltamethrin (Bayer Crop Science, Monheim am Rhein, Germany).

Main Article

1Current affilations: Natural Resources Institute, Chatham Maritime, Kent, UK; and University of Sussex, Brighton, UK.