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Volume 14, Number 11—November 2008

New Foci of Buruli Ulcer, Angola and Democratic Republic of Congo

Kapay Kibadi, Mbutu Panda, Jean-Jacques Muyembe Tamfum, Alexandra G. Fraga, Adhemar Longatto Filho, Gladys Anyo, Jorge Pedrosa, Yoshinori Nakazawa, Patrick Suykerbuyk, Wayne M. Meyers, and Françoise PortaelsComments to Author 
Author affiliations: Institute of Tropical Medicine, Antwerp, Belgium (K. Kibadi, G. Anyo, P. Suykerbuyk, F. Portaels); University of Kinshasa, Kinshasa, Democratic Republic of Congo (K. Kibadi, M. Panda); Institut National de Recherche Biomédicale, Kinshasa (K. Kibadi, J.-J. M. Tamfum); University of Minho, Braga, Portugal (A.G. Fraga, A.L. Filho, J. Pedrosa); University of Kansas, Lawrence, Kansas, USA (Y. Nakazawa); Armed Forces Institute of Pathology, Washington, DC, USA (W.M. Meyers);

Main Article


Characteristics of 3 Buruli ulcer patients infected along the Kwango/Cuango River, DRC and Angola*

Characteristic Patient 1 Patient 2 Patient 3
Age, y, sex 30, M 28, M 13, F
Origin Kinshasa, DRC Kinshasa, DRC Kinshasa, DRC
Location where infected
Kafufu/Luremo, Angola
Kafufu/Luremo, Angola
Kasongo-Lunda, DRC
Patient delay,† y 2 2.5 2.5
Date of first symptoms 2002 Oct 2003 Jan 2003 Jan
Date care was sought
2004 Sep
2005 Jun
2005 Jul
Type Ulcer Ulcer Ulcer
Size, cm2 320 150 896
Right thigh
Right arm
Left leg
Test results
Ziehl-Neelsen staining + + +
IS2404 PCR + + +
Histopathologic changes
Extensive areas of necrosis with clumps of AFB
Duration of hospitalization, mo 3 6 7
Follow-up period with no relapse, mo 42 30 28
Outcome Cured Cured Cured

*DRC, Democratic Republic of Congo; +, positive; –, negative; IS, insertion sequence; ND, not done; AFB, acid-fast bacilli.
†Time between appearance of first signs or symptoms and care being sought at a medical center.

Main Article

Page created: July 16, 2010
Page updated: July 16, 2010
Page reviewed: July 16, 2010
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