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Volume 14, Number 11—November 2008


Multidrug- and Extensively Drug-Resistant Tuberculosis, Germany

Barbara Eker, Johannes Ortmann, Giovanni B. Migliori, Giovanni Sotgiu, Ralf Muetterlein, Rosella Centis, Harald Hoffmann, Detlef Kirsten, Tom Schaberg, Sabine Ruesch-Gerdes, Christoph LangeComments to Author , and for the German TBNET Group
Author affiliations: Research Center Borstel, Borstel, Germany (B. Eker, S. Ruesch-Gerdes, C. Lange); Karl-Hansen-Clinic, Bad Lippspringe, Germany (J. Ortmann); World Health Organization Collaborating Center for TB and Lung Diseases, Tradate, Italy (G.B. Migliori, R. Centis); Sassari University, Sassari, Italy (G. Sotgiu); Regional Hospital, Pasberg, Germany (R. Muetterlein); Asklepios-Hospital, Gauting, Germany (H. Hoffmann); Hospital Großhansdorf, Großhansdorf, Germany (D. Kirsten); Deakoness Hospital, Rotenburg, Germany (T. Schaberg);

Main Article

Table 3

TB treatment outcomes in study patients not previously treated for TB compared with those treated previously for TB*

Treatment outcomes No. (%) patients not treated previously, n = 84 No. (%) patients treated previously, n = 100 p value 95% CI
Cured 40 (47.6) 42 (42) 0.49 −0.09 to 0.19
Completed 8 (9.5) 19 (19) 0.05 −0.19 to −0.001
Successful treatment (cured + completed) 48 (57) 61 (61) 0.58 −0.18 to 0.1
Died 7 (8.3) 8 (8) 1 −0.07 to 0.07
Failure 1 (1.19)
Treatment failure (death or failure) 8 (9) 8 (8) 0.8 −0.07 to 0.09
Default 1 (1)
Transferred out 13 (15.5) 12 (12) 0.55 −0.06 to 0.12
Uncertain outcome (default + transferred out) 13 (15.5) 13 (13) 0.69 −0.08 to 0.12
Still receiving treatment
15 (17.9)
18 (18)
−0.12 to 0.1
*TB, tuberculosis; CI, confidence interval.

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1Additional German Tuberculosis Network European Trials group (TBNET) contributors: R. Eberhardt, Thorax-Clinic-Heidelberg, Heidelberg; A. Esselmann, Pulmonary Clinic, Hemer; H. Flick, Charité, Berlin; M. Hamm, Hospital Diekholzen, Diekholzen; P. Hammerl, Hospital Immenhausen, Immenhausen; H. Hang, Hospital Schillerhöhe, Schillerhöhe; P. Hannemann, Deakoness Hospital, Neustadt; D. Hillemann, Research Center Borstel, Borstel; B. Kretz, Asklepios Hospital, Gauting; C. Laumanns, Bethania Hospital, Solingen; G. Liebetrau, Lostau Hospital, Lostau; S. Ott, Helios Clinic Emil von Behring, Berlin; A. Paulick, Pulmonary Clinic-Coswig, Coswig; M.W. Pletz, Hannover Medical School, Hannover; M. Rau, Pulmonary Clinic, Wangen; G. Rohde, Bergmannsheil Hospital, Bochum; A. de Roux, Evangelische Lungenklinik, Berlin; C. Schaudt, Hospital St. Blasien, St. Blasien; K-D.Schneider, Pulmonary Clinic, Hannover-East, Hannover; S. Stenger, University Hospital, Ulm; D. Wagner, University Hospital, Freiburg; and T. Wolf, University Hospital, Frankfurt.