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Volume 14, Number 4—April 2008


Emericella quadrilineata as Cause of Invasive Aspergillosis

Paul E. Verweij*Comments to Author , János Varga†‡, Jos Houbraken†, Antonius J.M.M. Rijs*, Frans M. VerduynLunel*, Nicole M.A. Blijlevens*, Yvonne R. Shea§, Steven M. Holland§, Adilia Warris*, Willem J. G. Melchers*, and Robert A. Samson†
Author affiliations: *Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; †Centraal Bureau voor Schimmelcultures Fungal Biodiversity Centre, Utrecht, the Netherlands,; ‡University of Szeged, Szeged, Hungary; §National Institutes of Health, Bethesda, Maryland, USA;

Main Article


Antifungal activities against Emericella nidulans and E. quadrilineata

Drug MIC, mean
E. nidulans (n = 12) E. quadrilineata (n = 12)
Amphotericin B 2.5 0.5 p<0.05
Itraconazole 0.07 0.13 NS
Voriconazole 0.26 0.39 p<0.05
Posaconazole 0.25 0.22 p<0.05
Caspofungin† 0.32 1.83 p<0.05
Terbinafine 0.01 0.009 NS

*NS, not significant.
†Mean minimum effective concentration was compared.

Main Article