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Volume 14, Number 9—September 2008
Dispatch

Highly Pathogenic Avian Influenza Virus (H5N1) Isolated from Whooper Swans, Japan

Yuko Uchida, Masaji Mase, Kumiko Yoneda, Atsumu Kimura, Tsuyoshi Obara, Seikou Kumagai, Takehiko SaitoComments to Author , Yu Yamamoto, Kikuyasu Nakamura, Kenji Tsukamoto, and Shigeo Yamaguchi
Author affiliations: National Institute of Animal Health, Kannondai, Japan (Y. Uchida, M. Mase, T. Saito, Y. Yamamoto, K. Nakamura, K. Tsukamoto, S. Yamaguchi); Japan Wildlife Research Center, Taito-ku, Tokyo, Japan (K. Yoneda); Akita Animal Hygiene Service Center of Akita Prefecture, Akita, Japan ( A. Kimura, T. Obara, S. Kumagai);

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Figure 2

Phylogenetic tree constructed based on the hemagglutinin (HA) 1 region (966 bp) of the HA gene of the highly pathogenic avian influenza viruses (H5N1). Clade designation follows the criteria proposed by the World Health Organization/World Organisation for Animal Health/Food and Agriculture Organization H5N1 Evolution Working Group (8). Representative strains of the previous highly pathogenic avian influenza outbreaks in Japan are in boldface. Scale bar represents number of nucleotide substitution per site.

Figure 2. Phylogenetic tree constructed based on the hemagglutinin (HA) 1 region (966 bp) of the HA gene of the highly pathogenic avian influenza viruses (H5N1). Clade designation follows the criteria proposed by the World Health Organization/World Organisation for Animal Health/Food and Agriculture Organization H5N1 Evolution Working Group (8). Representative strains of the previous highly pathogenic avian influenza outbreaks in Japan are in boldface. Scale bar represents number of nucleotide substitution per site.

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References
  1. Ellis  TM, Bousfield  RB, Bissett  LA, Dyrting  KC, Luk  GS, Tsim  ST, Investigation of outbreaks of highly pathogenic H5N1 avian influenza in waterfowl and wild birds in Hong Kong in late 2002. Avian Pathol. 2004;33:492–505. DOIPubMedGoogle Scholar
  2. Chen  H, Smith  GJ, Zhang  SY, Qin  K, Wang  J, Li  KS, Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature. 2005;436:191–2. DOIPubMedGoogle Scholar
  3. Liu  J, Xiao  H, Lei  F, Zhu  Q, Qin  K, Zhang  XW, Highly pathogenic H5N1 influenza virus infection in migratory birds. Science. 2005;309:1206. DOIPubMedGoogle Scholar
  4. Weber  S, Harder  T, Starick  E, Beer  M, Werner  O, Hoffmann  B, Molecular analysis of highly pathogenic avian influenza virus of subtype H5N1 isolated from wild birds and mammals in northern Germany. J Gen Virol. 2007;88:554–8. DOIPubMedGoogle Scholar
  5. Ducatez  MF, Olinger  CM, Owoade  AA, Tarnagda  Z, Tahita  MC, Sow  A, Molecular and antigenic evolution and geographical spread of H5N1 highly pathogenic avian influenza viruses in western Africa. J Gen Virol. 2007;88:2297–306. DOIPubMedGoogle Scholar
  6. Chen  H, Li  Y, Li  Z, Shi  J, Shinya  K, Deng  G, Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China. J Virol. 2006;80:5976–83. DOIPubMedGoogle Scholar
  7. Teifke  JP, Klopfleisch  R, Globig  A, Starick  E, Hoffmann  B, Wolf  PU, Pathology of natural infections by H5N1 highly pathogenic avian influenza virus in mute (Cygnus olor) and whooper (Cygnus cygnus) swans. Vet Pathol. 2007;44:137–43. DOIPubMedGoogle Scholar
  8. World Health Organization. 2007. Epidemic and Pandemic Alert and Response (EPR): Towards a unified nomenclature system for the highly pathogenic H5N1 avian influenza viruses [cited 2008 May 2] Available from http://www.who.int/csr/disease/influenza/nomen.ppt
  9. World Health Organization. Antigenic and genetic characteristics of (H5N1) viruses and candidate (H5N1) vaccine viruses developed for potential use as human vaccines [cited 2008 May 2]. Available from http://www.who.int/csr/disease/avian_influenza/guidelines/H5VaccineVirusUpdate20080214.pdf
  10. Ministry of the Environment, Government of Japan. Press release: preliminary results of 39th national survey of wild ducks and geese [in Japanese]. 2008 Apr 30 [cited 2008 May 2]. Available from http://www.env.go.jp/press/press.php?serial=9649
  11. Natural Parks Foundation. Seasons of Lake Towada. [in Japanese]. Updated 2008 Apr 25 [cited 2008 May 2]. Available from http://www.bes.or.jp/park/towada/now/towada_koyomi.htm
  12. Kanai  Y, Sato  F, Ueta  M, Minton  J, Higuchi  H, Soma  M, The migration routes and important rest sites of whooper swans satellite-tracked from northern Japan. Strix. 1997;15:1–3.
  13. Yamashina Institute for Ornithology. Atlas of Japanese migratory birds from 1961 to 1995. Yamashina (Japan): Bird Migration Research Center; 2002.
  14. Sturm-Ramirez  KM, Hulse-Post  DJ, Govorkova  EA, Humberd  J, Seiler  P, Puthavathana  P, Are ducks contributing to the endemicity of highly pathogenic H5N1 influenza virus in Asia? J Virol. 2005;79:11269–79. DOIPubMedGoogle Scholar

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