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Volume 15, Number 2—February 2009
Letter

Systemic Infection with Enteric Adenovirus in Immunocompetent Child with Haemophilus influenzae Disease

Nino KhetsurianiComments to Author , Suxiang Tong, Xiaoyan Lu, Shannon Reed, Dean D. Erdman, Angela P. Campbell1, Krongkaew Supawat, Sahas Liamsuwan, Narayanan Jothikumar, and Sonja J. Olsen2
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N. Khetsuriani, S. Tong, X. Lu, S. Reed, D. Erdman, A. Campbell, N. Jothikumar); National Institute of Health, Nonthaburi, Thailand (K. Supawat); Queen Sirikit National Institute of Child Health, Bangkok, Thailand (S. Liamsuwan); International Emerging Infections Program, Nonthaburi (S. Olsen)

Main Article

Table

Clinical course of illness in 10-month-old boy with systemic infection with enteric adenovirus and Haemophilus influenzae disease, Thailand, 2003–2004*

Date, 2003 Events
Dec 7 Patient hospitalized with 6-day history of fever >38°C and somnolence; blood culture positive for Hemophilus influenzae; isolate not typed (unavailable for further characterization)
Dec 9 CSF results: pleocytosis (2,710 leukocytes/mm3, 94% neutrophils); protein 178 mg/dL; glucose 11 mg/dL; CSF culture positive for H. influenzae; CSF Gram stain positive for gram-negative coccobacilli; antimicrobial drug treatment (ceftriaxone) started
Dec 11 New onset seizures, ataxia, and maculopapular rash on entire trunk and all extremities; no diarrhea or respiratory symptoms; brain ultrasound scan results within normal limits; anticonvulsant therapy (phenobarbital) started
Dec 12 CSF results: pleocytosis (100 leukocytes/mm3, 60% neutrophils, 40% monocytes); protein 131.6 mg/dL; glucose 31 mg/dL; CSF bacterial culture, results negative; CSF Gram stain results negative; patient enrolled in the encephalitis study; initial specimens for the study collected
Dec 22 Brain ultrasound scan results within normal limits; antimicrobial drug treatment (ceftriaxone) discontinued
Dec 23 CSF bacterial culture results negative; CSF Gram stain results negative; anticonvulsant therapy (phenobarbital) discontinued
Dec 27 Patient discharged in improved condition; discharge diagnosis: H. influenzae meningitis and septicemia
Jan 7† Follow-up visit: full recovery without sequelae; convalescent-phase serum specimen obtained

*CSF, cerebrospinal fluid.
†2004.

Main Article

1Current affiliation: University of Washington, Seattle, Washington, USA.

2Current affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Page created: December 08, 2010
Page updated: December 08, 2010
Page reviewed: December 08, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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