Volume 15, Number 7—July 2009
Dispatch
Recurrent Lymphocytic Meningitis Positive for Herpes Simplex Virus Type 2
Table 1
Presence of HSV type 2 DNA in CSF, leukocyte count, and timing of CSF samples in 22 patients with recurrent lymphocytic meningitis, through December 2007, Finland*
Patient no. | Age, y | No. episodes | Period (first episode–latest episode) | HSV-2 DNA in CSF | Leukocyte counts and timing of CSF samples in PCR-tested cases |
---|---|---|---|---|---|
1 | 29 | 7 | 2000–2004 | NT, P, NP, NT, NP, NP, NP | 44,† 18,‡ 4,‡ 2,‡ 1§ |
2 | 55 | 9 | 1985–2004 | NT, NT, NT, NT, NT, P, P, NP, NP | 219,§ 221,§ 9,† 3† |
3 | 44 | 4 | 1990–1998 | NT, NT, NT, P | 310§ |
4 | 43 | 4 | 1988–2000 | NT, NT, NT, P | 790§ |
5 | 33 | 4 | 1994–1998 | NT, P, P, P | 1,410,§ ¶,§ 73§ |
6 | 32 | 4 | 1996–2002 | P, NP, NP, NP | 164,§ 64,† 32,† 93† |
7 | 48 | 5 | 1979–2002 | NT, NT, NT, P, NT | 196§ |
8 | 33 | 4 | 1998–2005 | NT, P, NP, NP | 360,† 238,§ 239# |
9 | 36 | 13 | 1990–2007 | NT, NT, NT, NT, NT, NT, NT, NT, P, NP, NP, NP, NP | 195,§ 2,† 0,† 260,§ 1‡ |
10 | 40 | 4 | 1990–1994 | NT, NT, P, NT | 40¶ |
11 | 47 | 2 | 2001–2003 | P, NP | 1,006,§ 790§ |
12 | 40 | 2 | 1989–1997 | NT, P | 325§ |
13 | 36 | 2 | 2001–2004 | P, P | 592,§ 620§ |
14 | 38 | 2 | 1991–1996 | NT, P | 92§ |
15 | 51 | 3 | 1975–1998 | NT, NT, P | 680† |
16 | 38 | 7 | 1992–2006 | NT, P, NT, NP, NT, NT, P | 160,† 16,‡ 106§ |
17 | 51 | 3 | 1984–1998 | NT, NT, P | 360† |
18 | 39 | 3 | 1989–2004 | NT, NT, P | 172§ |
19 | 45 | 5 | 1980–2004 | NT, NT, NT, P,P | 350,§ 203§ |
20 | 25 | 2 | 2002–2004 | P, NP | 1,350,§ 430§ |
21 | 33 | 4 | 1995–2007 | P,P, P, NT | 720,§ 306,§ ¶§ |
22 | 38 | 2 | 1990–1999 | NT, P | 645† |
*HSV, herpes simplex virus; CSF, cerebrospinal fluid; NT, HSV DNA not tested; P, HSV-2 DNA present in CSF; NP, HSV-2 DNA not present in CSF. Boldface indicates HSV-2 DNA present in the sample.
†CNF sample taken 24–48 h after first symptoms.
‡CSF sample taken within 24 h of the first symptoms.
§CSF sample taken 2–5 days after first symptoms.
¶Leukocyte count or timing of the sample not known.
#CSF sample taken >5 days after first symptoms.