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Volume 15, Number 7—July 2009

Dispatch

Recurrent Lymphocytic Meningitis Positive for Herpes Simplex Virus Type 2

Katariina Kallio-LaineComments to Author , Mikko Seppänen, Hannu Kautiainen, Marja-Liisa Lokki, Maija Lappalainen, Ville Valtonen, Markus Färkkilä, and Eija Kalso
Author affiliations: Helsinki University Central Hospital, Helsinki, Finland (K. Kallio-Laine, M. Seppänen, M. Lappalainen, V. Valtonen, M. Färkkilä, E. Kalso); Orton Orthopedic Hospital, Helsinki (H. Kautiainen); Haartman Institute, University of Helsinki, Helsinki (M.-L. Lokki)

Main Article

Table 1

Presence of HSV type 2 DNA in CSF, leukocyte count, and timing of CSF samples in 22 patients with recurrent lymphocytic meningitis, through December 2007, Finland*

Patient no. Age, y No. episodes Period 
(first episode–latest episode) HSV-2 DNA in CSF Leukocyte counts and timing of CSF samples in PCR-tested cases
1 29 7 2000–2004 NT, P, NP, NT, NP, NP, NP 44,† 18,‡ 4,‡ 2,‡ 1§
2 55 9 1985–2004 NT, NT, NT, NT, NT, P, P, NP, NP 219,§ 221,§ 9,† 3†
3 44 4 1990–1998 NT, NT, NT, P 310§
4 43 4 1988–2000 NT, NT, NT, P 790§
5 33 4 1994–1998 NT, P, P, P 1,410,§ ¶,§ 73§
6 32 4 1996–2002 P, NP, NP, NP 164,§ 64,† 32,† 93†
7 48 5 1979–2002 NT, NT, NT, P, NT 196§
8 33 4 1998–2005 NT, P, NP, NP 360,† 238,§ 239#
9 36 13 1990–2007 NT, NT, NT, NT, NT, NT, NT, NT, P, NP, NP, NP, NP 195,§ 2,† 0,† 260,§ 1‡
10 40 4 1990–1994 NT, NT, P, NT 40
11 47 2 2001–2003 P, NP 1,006,§ 790§
12 40 2 1989–1997 NT, P 325§
13 36 2 2001–2004 P, P 592,§ 620§
14 38 2 1991–1996 NT, P 92§
15 51 3 1975–1998 NT, NT, P 680†
16 38 7 1992–2006 NT, P, NT, NP, NT, NT, P 160,† 16,‡ 106§
17 51 3 1984–1998 NT, NT, P 360†
18 39 3 1989–2004 NT, NT, P 172§
19 45 5 1980–2004 NT, NT, NT, P,P 350,§ 203§
20 25 2 2002–2004 P, NP 1,350,§ 430§
21 33 4 1995–2007 P,P, P, NT 720,§ 306,§ ¶§
22 38 2 1990–1999 NT, P 645†

*HSV, herpes simplex virus; CSF, cerebrospinal fluid; NT, HSV DNA not tested; P, HSV-2 DNA present in CSF; NP, HSV-2 DNA not present in CSF. Boldface indicates HSV-2 DNA present in the sample.
†CNF sample taken 24–48 h after first symptoms.
‡CSF sample taken within 24 h of the first symptoms.
§CSF sample taken 2–5 days after first symptoms.
¶Leukocyte count or timing of the sample not known.
#CSF sample taken >5 days after first symptoms.

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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.

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