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Volume 15, Number 7—July 2009
Dispatch

Eczema Herpeticum and Clinical Criteria for Investigating Smallpox

David A. BoydComments to Author , Leonard C. Sperling, and Scott A. Norton
Author affiliations: Naval Hospital Jacksonville, Jacksonville, Florida, USA (D.A. Boyd); Uniformed Services University, Bethesda, Maryland, USA (L.C. Sperling, S.A. Norton)

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Table

Major clinical criteria for smallpox*

Febrile prodrome Occurring 1–4 days before rash onset; fever >101ºF; and >1 of the following: prostration, headache, backache, chills, vomiting, or severe abdominal pain.
Classic smallpox lesions Deep-seated, firm/hard, round, well-circumscribed vesicles or pustules; as they evolve, lesions may become umbilicated or confluent.
Lesions in same stage of development On any single part of the body (e.g., face or arm); all lesions are in the same stage of development (i.e., all are vesicles or pustules).

*Source (3).

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References
  1. Seward  JF, Galil  K, Damon  I, Norton  SA, Rotz  L, Schmid  S, Development and experience with an algorithm to evaluate suspected smallpox cases in the United States. Clin Infect Dis. 2004;39:1477–83. DOIPubMedGoogle Scholar
  2. Centers for Disease Control and Prevention. Smallpox case definitions [cited 2008 Sept 24]. Available from http://www.bt.cdc.gov/agent/smallpox/diagnosis/casedefinition.asp
  3. Centers for Disease Control and Prevention. Evaluating patients for smallpox [cited 2007 Dec 4]. Available from http://www.bt.cdc.gov/agent/smallpox/diagnosis/pdf/spox-poster-full.pdf
  4. Hutchins  SS, Sulemana  I, Heilpern  KL, Schaffner  W, Wax  G, Lerner  EB, Performance of an algorithm for assessing smallpox risk among patients with rashes that may be confused with smallpox. Clin Infect Dis. 2008;46:S195–203. DOIPubMedGoogle Scholar
  5. Danzl  DF, Pozos  RS. Accidental hypothermia. N Engl J Med. 1994;331:1756–60. DOIPubMedGoogle Scholar
  6. Centers for Disease Control and Prevention. Generalized vesicular or pustular rash illness protocol [cited 2007 Dec 4]. Available from http://www.bt.cdc.gov/agent/smallpox/response-plan/files/annex-4-rash-color.pdf
  7. Peres Bota  D, Lopes Ferreira  F, Melot  C, Vincent  JL. Body temperature alterations in the critically ill. Intensive Care Med. 2004;30:811–6. DOIPubMedGoogle Scholar
  8. Levy  MM, Fink  MP, Marshall  JC, Abraham  E, Angus  D, Cook  D, 2001 SCCM ESICM ACCP ATS SIS International Sepsis Definitions Conference. Crit Care Med. 2003;31:1250–6. DOIPubMedGoogle Scholar
  9. Slifka  MK, Hanifin  JM. Smallpox: the basics. Dermatol Clin. 2004;22:263–74. DOIPubMedGoogle Scholar
  10. Wollenberg  A, Zoch  C, Wetzel  S, Plewig  G, Przybilla  B. Predisposing factors and clinical features of eczema herpeticum: a retrospective analysis of 100 cases. J Am Acad Dermatol. 2003;49:198–205. DOIPubMedGoogle Scholar
  11. Stalkup  JR, Yeung-Yue  K, Brentjens  M, Tyring  SK. Human herpesviruses. In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology, vol 1. Philadelphia: Mosby; 2003. p. 1235–52.
  12. Vesely  DL, Mastrandrea  P, Samson  C, Argyelan  G, Charvit  S. Post-herpes encephalitic anterior pituitary insufficiency with hypothermia and hypotension. Am J Med Sci. 2000;320:273–7. DOIPubMedGoogle Scholar
  13. Balk  RA. Severe sepsis and septic shock. Definitions, epidemiology, and clinical manifestations. Crit Care Clin. 2000;16:179–92. DOIPubMedGoogle Scholar

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Page created: November 09, 2010
Page updated: November 09, 2010
Page reviewed: November 09, 2010
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