Volume 16, Number 6—June 2010
Human Infection with Lymphocytic Choriomeningitis Virus
To the Editor: I read with great interest the article regarding lymphocytic choriomeningitis virus (LCMV) meningitis in a New York City resident (1). The authors’ conclusion that there is a need to ascertain the true incidence of LCMV infection is worthy of underscoring. Nearly 15 years ago, in this same journal, we described congenital LCMV as an unrecognized teratogen and recommended further “research to define the frequency of LCMV” (2). Five years later, we reiterated that recommendation when reporting acquired LCMV meningoencephalitis in an adolescent from Tucson, Arizona (3). Despite, or because of, the lack of prospective studies, the fact that this author has accrued data regarding >60 congenitally infected infants from all geographic areas in the United States during the past 15 years reinforces the concept that LCMV is a neglected pathogen whose time for more extensive study has indeed come.
- Asnis DS, Muana O, Kim DG, Garcia M, Rollin PE, Slavinski S. Lymphocytic choriomeningitis virus meningitis, New York, NY, USA, 2009. Emerg Infect Dis. 2010;16:328–30.
- Barton LL, Peters CJ, Ksiazek TG. Congenital lymphocytic choriomeningitis virus: an unrecognized teratogenic pathogen. Emerg Infect Dis. 1995;1:152–3.
- Barton LL, Hyndman NJ. Lymphocytic choriomeningitis virus: reemerging central nervous system pathogen. Pediatrics. 2000;105:e35–6.