Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 16, Number 8—August 2010


Outbreak of Corynebacterium pseudodiphtheriticum Infection in Cystic Fibrosis Patients, France

Fadi Bittar1, Carole Cassagne1, Emmanuelle Bosdure, Nathalie Stremler, Jean-Christophe Dubus, Jacques Sarles, Martine Reynaud-Gaubert, Didier Raoult, and Jean-Marc RolainComments to Author 

Author affiliations: Université de la Méditerranée, Marseille, France (F. Bittar, C. Cassagne, D. Raoult, J.-M. Rolain); Hôpital Timone, Marseille (E. Bosdure, N. Stremler, J.-C. Dubus, J. Sarles); Hôpital Sainte-Marguerite, Marseille (M. Reynaud-Gaubert)

Main Article

Patient Age/sex Isolate Symptoms Treatment Sample Other isolated pathogens Identification
rpoB PCR
Result % Code Result % Accession no. Result Score value†
A 4 mo/F A1 Cough Unknown BAL SA, fungi CP 96.8 3001004 CP 99 AY492232 CP 1,815 R S
A2 None Unknown BAL None CP 96.8 3001004 CP 99 AY492232 CP 2,492 R S
A3 Unknown Unknown BAL None CP 99 7001004 CP 99 AY492232 CP 1,950 R I
B 35 mo/F B Rhinitis None NPA HI CP 96.8 3001004 CP 97 AY492232 CP 2,051 R S
C 5 y/M C None None SP SA CP 84.6 3003004 CP 100 AY492232 CP 2,477 S S
D 10 y/F D None None SP CAL CP 94.9 3101004 CP 100 AY492232 CP 2,272 I S
E 13 mo E Unknown Unknown BAL None Br UIP 5101764 CP 100 AY492232 CP 2,353 S S
F 2 y/M F Cough AMX and SXT BAL SA, fungi CP 94.9 3101004 CP 99 AY492232 CP 2,416 S I
G 15 mo/F G1 Cough AUG NPA SA CP 97.9 5101007 CP 97 AY492232 CP 2,246 R S
G2 None None NPA None CPQ 88 3000004 CP 100 AY492232 CP 2,069 R S
H 35 mo/F H Rhinitis, cough AMX NPA SA CP 92.3 1021004 CP 99 AY492232 CP 1,914 R S
I 2 mo/F I1 Cough None NPA EC CP 1.1 2001004 CP 98 AY492232 CP 2,444 R S
I2 Cough None NPA EC CP 95 3101004 CP 98 AY492232 CP 2,406 S S
J 9 y/F J Cough SXT then AMX SP None CP 94.9 3101004 CP 98 AY492232 CP 2,461 S S
K 21 mo/M K1 Rhinitis, cough AUG NPA BC CP 97.9 5101004 CP 98 AY492232 CP 2,386 R S
K2 Rhinitis AUG NPA HI CP 94.9 3101004 CP 98 AY492232 CP 2,044 R S
L 3 y/M L Cough SXT NPA BC CP 94.9 3101004 CP 98 AY492232 CP 2,098 R S
M 16 y/F M Rhinitis None SP None CP 96.8 3001004 CP 98 AY492232 CP 1,787 S R

*MALDI-TOF MS, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; Ery, erythromycin; SXT, cotrimoxazole; BAL, bronchoalveolar fluid; SA, Staphylococcus aureus; CP, Corynebacterium pseudodiphtheriticum; R, resistant; S, sensitive; I, intermediary; NPA, nasopharyngeal aspirate; SP, sputum sample; HI, Haemophilus influenzae; CAL, Candida albicans; Br, Brevibacterium sp; UIP, uninterpretable pattern; AMX, amoxicillin; AUG, amoxicillin and clavulanic acid; CPQ, Corynebacterium propinquum; EC, Escherichia coli; BC, Branhamella catarrhalis.
†Score value represents the mean of 3 different analyses.

Main Article

1These authors contributed equally to this article.