Volume 17, Number 1—January 2011
Letter
Class D OXA-48 Carbapenemase in Multidrug-Resistant Enterobacteria, Senegal
Olivier Moquet
, Coralie Bouchiat, Alfred Kinana, Abdoulaye Seck, Omar Arouna, Raymond Bercion, Sebastien Breurec, and Benoit Garin
, Coralie Bouchiat, Alfred Kinana, Abdoulaye Seck, Omar Arouna, Raymond Bercion, Sebastien Breurec, and Benoit Garin
Table
Resistance genes and carbapenem MICs of 11 Enterbacteriaceae isolates, Senegal, 2008–2009*
| Isolate | Species | Origin† | Resistance genes |
MIC (µg/mL) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| blaOXA-48 | blaCTX-M-15 | blaOXA-1 | blaTEM | aac-6′-Ib | qnr | tet | dfr | IPM | MEM | ERT | ||||
| 17176 | Klebsiella pneumoniae | 1 | + | + | – | – | – | – | A,D | – | 1 | 0.38 | 1.5 | |
| 22184 | K. pneumoniae‡ | 2 | + | + | + | + | cr | S | A | A1 | 1 | 0.38 | 1.5 | |
| 20254 | K. pneumoniae‡ | 3 | + | + | + | + | cr | S | A | A1 | 1 | 0.38 | 1.5 | |
| 10243 | K .pneumoniae‡ | 3 | + | + | + | + | cr | S | A | A1 | 1 | 0.38 | 1.5 | |
| 19220 | K. pneumoniae | 2 | + | + | + | + | cr | B | A,D | – | 0.5 | 0.19 | 0.75 | |
| 18212 | K. pneumoniae | 2 | + | – | – | – | – | – | – | – | 3 | 2 | 12 | |
| 18220 | K. pneumoniae | 3 | + | + | – | + | – | S | D | – | 1 | 0.38 | 1.5 | |
| 06003 | K. pneumoniae | 4 | + | – | – | – | – | – | – | – | 2 | 0.25 | 0.75 | |
| HPD | Enterobacter cloacae | 3 | + | + | + | + | cr | B,S | B | – | 4 | 3 | 8 | |
| 20247 | Enterobacter sakazakii | 5 | + | + | + | + | cr | – | – | – | 0.5 | 1 | 3 | |
| 24246 | Escherichia coli | 4 | + | + | + | – | cr | S | – | – | 2 | 0.5 | 2 | |
| J53 | E. coli | – | – | – | – | – | – | – | – | 0.12 | 0.03 | 0.03 | ||
| TC | E. coli | + | – | – | – | – | – | – | – | 0.5 | 0.19 | 0.75 | ||
*IPM, imipenem; MEM, meropenem; ERT, ertapenem; TC, transconjugants.
†Origin: 1, postsurgical visceral infection; 2, postsurgical orthopedic infection; 3, nosocomial urinary tract infection; 4, community-acquired urinary tract infection; 5, omphalocele infection.
‡Clonally related isolates.
Page created: June 30, 2011
Page updated: June 30, 2011
Page reviewed: June 30, 2011
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