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Volume 17, Number 10—October 2011
Dispatch

Clostridium difficile Infection in Outpatients, Maryland and Connecticut, USA, 2002–2007

Jon Mark HirshonComments to Author , Angela D. Thompson, Brandi M. Limbago, L. Clifford McDonald, Michelle Bonkosky, Robert Heimer, James I. Meek, Volker Mai, and Christopher R. Braden
Author affiliations: University of Maryland School of Medicine, Baltimore, Maryland, USA (J.M. Hirshon); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.D. Thompson, B. Limbago, L.C. McDonald, M. Bonkosky, C. Braden); Yale School of Medicine, New Haven, Connecticut, USA (R. Heimer, J. Meek); University of Florida, Gainesville, Florida, USA (V. Mai)

Main Article

Table 1

Patient risk factors for CDI compared with those of other patients with diarrhea without CDI, Maryland and Connecticut, USA, 2002−2007*

Risk factor No. (%) patients with CDI, n = 43 No. (%) patients with diarrhea but not CDI, n = 1,048 p value†
Illnesses potentially affecting immune status
Lupus 1 (2.3) 4 (0.4) 0.06
Cancer under active treatment 3 (7.0) 40 (3.8) 0.30
HIV/AIDS 2 (4.7) 43 (4.1) 0.86
History of organ transplant 2 (4.7) 22 (2.1) 0.26
Chronic obstructive pulmonary disease (on prednisone)
1 (2.3)
NA
NA
Illnesses potentially affecting gastrointestinal function
Crohn disease 0 (0) 14 (1.3) 0.45
Ulcerative colitis
1 (2.3)
19 (1.8)
0.81
Prior bowel or ulcer surgery 6 (14.0) 69 (6.6) 0.06
Any medical or surgical condition 15 (34.9) 176 (16.8) 0.002
Hospitalized within prior month 14 (32.6) 92 (8.8) <0.001
Antimicrobial drug therapy within prior month 27 (62.8) 231 (22.0) <0.001
No hospitalization or antimicrobial drug therapy within prior month and no predisposing condition 7 (16.3) 698 (66.6) <0.001

*CDI, Clostridium difficile infection; NA, not available.
†Uncorrected χ2.

*CDI, Clostridium difficile infection; NA, not available.
†Uncorrected χ2.

*CDI, Clostridium difficile infection; NA, not available.
†Uncorrected χ2.

Main Article

Page created: September 26, 2011
Page updated: September 26, 2011
Page reviewed: September 26, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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