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Volume 17, Number 10—October 2011

Seroconversion to Pandemic (H1N1) 2009 Virus and Cross-Reactive Immunity to Other Swine Influenza Viruses

Ranawaka A.P.M. Perera, Steven Riley, Siu K. Ma, Hua-Chen Zhu, Yi Guan, and Joseph S.M. PeirisComments to Author 
Author affiliations: The University of Hong Kong, Hong Kong Special Administrative Region, People’s Republic of China (R.A.P.M. Perera, S.K. Ma, H.-C. Zhu, Y. Guan, J.S.M. Peiris); Imperial College, London, UK (S. Riley)

Main Article


Seroprevalence and GMT for swine influenza viruses of H1 subtype in prepandemic and postpandemic serum specimens from 28 persons who seroconverted for pandemic (H1N1) 2009, Hong Kong*

Virus Virus abbreviation Virus lineage
(abbreviation) No. (%) seroconverters†
Prepandemic Postpandemic Prepandemic Postpandemic
A/California/4/2009 (H1N1) Cal4 Pandemic (Pdm) 0 28 (100) 10.77 107.7
A/Swine/HK/4167/1999 (H1N1) Sw4167 Classical swine (CS) 6 (21) 26 (93) 17.24 121.9
A/Swine/HK/1304/2003 (H1N?) Sw1304 Classical swine reassortant (CSr) 7 (25) 24 (86) 16.41 105
A/Swine/HK/1110/2006 (H1N2) Sw1110 Triple reassortant (TRIG) 2 (7) 21 (75) 13.13 44.16
A/Swine/HK/NS29/2009 (H1N1) SwNS29 Eurasian avian-like (EA) 2 (7) 13 (46) 12.50 30.46
A/Swine/HK/1559/2008 (H1N1) Sw1559 Eurasian avian-like reassortant (EAr) 2 (7) 16 (57) 12.81 41.00
A/Swine/G/112/2007 (H1N1) Sw112 Eurasian avian-like (EA) 0 (0) 3 (11) 10.25 13.13
A/Swine/HK/201/2010 (H1N1) Sw201 TRIG reassortant
(TRIGr) 3 (11) 21 (75) 12.2 48.76
A/HK/400599/2008 (H1N1) 400599 Seasonal influenza 12 (43) 12 (43) 38.07 40.00

*GMT, geometric mean titer.
†Seroconverters were persons with antibody titer >40.

Main Article

Page created: September 26, 2011
Page updated: September 26, 2011
Page reviewed: September 26, 2011
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