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Volume 17, Number 4—April 2011


Hepatitis A Virus Vaccine Escape Variants and Potential New Serotype Emergence

Unai Pérez-Sautu1, M. Isabel Costafreda1, Joan Caylà, Cecilia Tortajada, Josep Lite, Albert Bosch, and Rosa M. PintóComments to Author 
Author affiliations: Author affiliations: University of Barcelona, Barcelona, Spain (U. Pérez-Sautu, M.I. Costafreda, A. Bosch, R.M. Pintó); Public Health Agency of Barcelona, Barcelona (J. Caylà, C. Tortajada); CatLab, Viladecavalls, Spain (J. Lite)

Main Article

Table 1

Amino acid substitutions in the VP1 protein observed in different strains isolated during the present study*

Strain Replacement Position*
MSM08-09-219 V → G 1166
MSM08-09-186 V → G 1166
V → A 1171
BCN60 Y → S 1181
MSM08-09-ClusterE R → T 1189
MSM08-09-144 A → V 1280
BCN31 A → E 1280

*Position strain HM175 (GenBank accession no. M14707). The first digit refers to the viral protein, i.e., 1 for VP1, and the following 3 digits refer to the amino acid position in the protein.

Main Article

1These authors contributed equally to this article.