Volume 17, Number 5—May 2011
Research
Evolution of New Genotype of West Nile Virus in North America
Allison R. McMullen, Fiona J. May, Li Li, Hilda Guzman, Rudy Bueno, James A. Dennett, Robert B. Tesh, and Alan D.T. Barrett
Table 2
Nucleotide sequence changes in West Nile virus NA/WN02 genotype, Upper Texas Gulf Coast, USA*
| Strain | Year | prM |
E |
NS2A |
NS3 |
NS4B |
NS5 |
3′ UTR |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 660 | 1442 | 2466 | 3774 | 4146 | 4803 | 6138 | 6238 | 6426 | 6996 | 7938 | 9352 | 10851 | ||||||||
| NY99 | 1999 | C | U | C | U | A | C | C | C | C | C | U | C | A | ||||||
| Bird 114 | 2002 | U | C† | U | U | G | U | U | U | U | U | C | U | G | ||||||
| M12214 | 2005 | U | C | U | U | G | U | U | U | · | U | C | U | G | ||||||
| TX5058 | U | C | U | U | G | U | U | U | U | U | C | U | G | |||||||
| TX5810 | 2006 | U | C | U | U | G | U | U | U | U | U | C | · | G | ||||||
| M6019 | U | C | U | U | G | U | U | U | U | U | C | · | G | |||||||
| TX 6276 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| TX 6647 | 2007 | U | C | U | U | G | U | U | U | U | U | C | U | G | ||||||
| TX6747 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| M19433 | U | C | U | U | G | U | U | U | · | U | C | U | G | |||||||
| TX7191 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| TX 7558 | 2008 | U | C | U | U | G | U | U | U | U | U | C | U | G | ||||||
| M 37012 | 2009 | · | C | U | U | G | U | U | · | U | U | C | U | G | ||||||
| M 37906 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| TX 7827 | U | C | U | U | G | U | U | U | U | U | C | U | G | |||||||
| M 39488 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| M 20140 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| M 20141 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
| M20122 | · | C | U | U | G | U | U | · | U | U | C | U | G | |||||||
*PrM, premembrane; E, envelope; NS, nonstructural; UTR, untranslated region. Values indicate nucleotide position within each gene. Dots indicate no change from NY99 isolate.
†Encodes for amino acid substitution E-V159A.
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