Volume 17, Number 5—May 2011
Dispatch
Genetic Characterization of West Nile Virus Lineage 2, Greece, 2010
Anna Papa, Tamás Bakonyi, Kyriaki Xanthopoulou, Ana Vázquez, Antonio Tenorio, and Norbert Nowotny
Table
Unique amino acid substitutions in the putative nonstructural proteins of the Nea Santa-Greece-2010 lineage 2 West Nile virus*
| Strain | Protein, aa position |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NS1 |
NS2B |
NS3 |
NS4B |
NS5 |
|||||||||||
| 44 | 88 | 119 | 11 | 249 | 14 | 23 | 32 | 49 | 113 | 190 | |||||
| Gr-10 (lin. 2) | Arg | Ile | Ile | Arg | Pro | Gly | Thr | Asn | Ala | Met | Arg | ||||
| Hu-04 (lin. 2) | Arg | Ile | Val | Arg | His | Ser | Thr | Asn | Thr | Val | Lys | ||||
| Other lin. 2 WNV strains | Lys | Met | Val | Lys | His | Ser† | Ala | Ser | Thr‡ | Val | Lys | ||||
| NY-99 (lin. 1) | Lys | Met | Val | Lys | Pro | Ser | Val | Glu | Thr | Val | Lys | ||||
| Rab-97 (lin. 3) | Arg | Ile | Val | Lys | Asn | Ser | Thr | Asp | Ser | Val | Lys | ||||
| Rus-98 (lin. 4) | Lys | Met | Val | Arg | Thr | Gly | Ser | Ser | Ser | Val | Lys | ||||
| Ind-80 (lin. 5) | Lys | Met | Val | Lys | Thr | Gly | Ala | Glu | Thr | Val | Lys | ||||
*NS, nonstructural protein; aa, amino acid; lin., lineage; Arg, arginine; Ile, isoleucine; Pro, proline; Gly, glycine; Thr, threonine; Asn, asparagine; Ala, alanine; Met, methionine; Val, valine; His, histidine; Lys, lysine; Ser, serine; WNV, West Nile virus. Abbreviations of strains are explained in the Figure legend. Boldface indicates the His→Pro substitution at aa position 249.
†Except SE-90, WNFCG, Mad-78, and Sarafend (Gly).
‡Except Mad-78 (Ala).
Page created: August 19, 2011
Page updated: August 19, 2011
Page reviewed: August 19, 2011
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