Volume 17, Number 5—May 2011
Dispatch
Genetic Characterization of West Nile Virus Lineage 2, Greece, 2010
Table
Unique amino acid substitutions in the putative nonstructural proteins of the Nea Santa-Greece-2010 lineage 2 West Nile virus*
Strain | Protein, aa position |
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NS1 |
NS2B |
NS3 |
NS4B |
NS5 |
|||||||||||
44 | 88 | 119 | 11 | 249 | 14 | 23 | 32 | 49 | 113 | 190 | |||||
Gr-10 (lin. 2) | Arg | Ile | Ile | Arg | Pro | Gly | Thr | Asn | Ala | Met | Arg | ||||
Hu-04 (lin. 2) | Arg | Ile | Val | Arg | His | Ser | Thr | Asn | Thr | Val | Lys | ||||
Other lin. 2 WNV strains | Lys | Met | Val | Lys | His | Ser† | Ala | Ser | Thr‡ | Val | Lys | ||||
NY-99 (lin. 1) | Lys | Met | Val | Lys | Pro | Ser | Val | Glu | Thr | Val | Lys | ||||
Rab-97 (lin. 3) | Arg | Ile | Val | Lys | Asn | Ser | Thr | Asp | Ser | Val | Lys | ||||
Rus-98 (lin. 4) | Lys | Met | Val | Arg | Thr | Gly | Ser | Ser | Ser | Val | Lys | ||||
Ind-80 (lin. 5) | Lys | Met | Val | Lys | Thr | Gly | Ala | Glu | Thr | Val | Lys |
*NS, nonstructural protein; aa, amino acid; lin., lineage; Arg, arginine; Ile, isoleucine; Pro, proline; Gly, glycine; Thr, threonine; Asn, asparagine; Ala, alanine; Met, methionine; Val, valine; His, histidine; Lys, lysine; Ser, serine; WNV, West Nile virus. Abbreviations of strains are explained in the Figure legend. Boldface indicates the His→Pro substitution at aa position 249.
†Except SE-90, WNFCG, Mad-78, and Sarafend (Gly).
‡Except Mad-78 (Ala).