Volume 17, Number 6—June 2011
Dispatch
Ciprofloxacin-Resistant Salmonella enterica Serotype Typhi, United States, 1999–2008
Table 2
Patient and isolate description, resistance to other antimicrobial agents, PFGE pattern, and travel reported for 9 ciprofloxacin-resistant Salmonella enterica serotype Typhi infections detected in the National Antimicrobial Resistance Monitoring System, United States, 1999–2008*
Patient no. (isolate) | Age, y/ sex | Site | Specimen collection year | Specimen source | Resistance to other agents | PFGE XbaI pattern† | PFGE BlnI pattern‡ | Travel§ |
---|---|---|---|---|---|---|---|---|
1 (MA-03) | 1/F | MA | 2003 | Blood | Cot, Fis, Nal, Tet | JPPX01.0026 | JPPA26.0110 | India |
2 (CA-05) | 2/F | CA | 2005 | Blood | Cot, Fis, Nal, Tet | JPPX01.0026 | JPPA26.0110 | India |
3 (CA-06) | 26/F | CA | 2006 | Blood | Nal | JPPX01.0506 | JPPA26.0187 | India |
4 (TX-06) | 8/M | TX | 2006 | Blood | Amp, Chl, Cot, Fis, Nal, Str | JPPX01.0465 | JPPA26.0170 | India, other |
5 (AZ-06) | 5/M | AZ | 2006 | Stool | Cot, Fis, Nal, Tet | JPPX01.0026 | JPPA26.0110 | India |
6 (NY-07) | 6/M | NYC | 2007 | Stool | Nal | JPPX01.0506 | JPPA26.0187 | India |
7 (CA-07) | 22/M | CA | 2007 | Stool | Cot, Fis, Nal, Tet | JPPX01.0026 | JPPA26.0110 | India |
8 (NJ-07) | 28/M | NJ | 2007 | Blood | Nal | JPPX01.0026 | JPPA26.0002 | India |
9 (LAC-07) | 48/F | LAC | 2007 | Blood | Nal | JPPX01.0506 | JPPA26.0187 | Unknown |
*PFGE, pulsed-field gel electrophoresis. State/local public health laboratories that submitted isolates: MA, Massachusetts; CA, California; TX, Texas; AZ, Arizona; NYC, New York City; NJ, New Jersey; LAC, Los Angeles County, California. Resistance to antimicrobial agents other than ciprofloxacin: Cot, trimethoprim–sulfamethoxazole; Fis, sulfamethoxazole or sulfisoxazole; Nal, nalidixic acid; Tet, tetracycline; Amp, ampicillin; Chl, chloramphenicol; Str, streptomycin.
†National Molecular Subtyping Network for Foodborne Disease Surveillance (PulseNet)–designated PFGE patterns using restriction enzyme XbaI (data as of 2009 Oct 21): JPPX01.0026, the most common XbaI pattern among 3,233 isolates with reported XbaI pattern in PulseNet, was detected in 486 (15.0%); JPPX01.0465 and JPPX01.0506 each were detected in 12 (0.4%) isolates.
‡PulseNet-designated PFGE patterns using restriction enzyme BlnI (data as of 2009 Oct 21): JPPA26.0002, the most common BlnI pattern among 409 isolates with reported BlnI pattern in PulseNet, was detected in 61 (14.9%) isolates; JPPA26.0110 was detected in 5 (1.2%), JPPA26.0187 was detected in 3 (0.7%), and JPPA26.0170 was detected in 1 (0.2%).
§Travel outside the United States reported in the 30 d before illness onset; patient 4 also traveled to Bangladesh and the United Arab Emirates.