Volume 17, Number 6—June 2011
Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
||Nal MICs,† μg/mL||Cip MICs,† μg/mL||QRDR mutation (no./no. tested)
|gyrB Leu465 (2/77)|
|C||119||>256||>256||128–>256||0.25||0.5||0.06–0.5||gyrA Phe83 (24/44)|
|gyrA Tyr83 (12/44)|
|gyrA Asn87 (4/44)|
|gyrA Gly87 (2/44)|
|gyrA Phe83 and parE Asn420 (2/44)|
|D||1||>256||8||gyrA Phe83, gyrA Asn87, and parC Ile80|
*Nal, nalidixic acid; Cip, ciprofloxacin; QRDR, quinolone resistance–determining region of the gyrA, gyrB, parC, and parE genes; WT, wild type.
†MICs of Nal and Cip were determined by Etest strips. MIC50, 50% below; MIC90, 90% below.
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