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Volume 17, Number 9—September 2011


Seroepidemiologic Study of Pandemic (H1N1) 2009 during Outbreak in Boarding School, England

Sandra Johnson, Chikwe IhekweazuComments to Author , Pia Hardelid, Nika Raphaely, Katja Hoschler, Alison Bermingham, Muhammad Abid, Richard G. Pebody, Graham Bickler, John T. Watson, and Éamonn O’Moore
Author affiliations: Author affiliations: Health Protection Agency, London, UK (S. Johnson, C. Ihekweazu, P. Hardelid, K. Hoschler, A. Bermingham, R. Pebody, G. Bickler, J. Watson); Health Protection Agency, Oxfordshire, UK (N. Raphaely, M. Abid, É. O’Moore)

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Table 3

Multivariable analysis of all study participants in relation to having ARI or serology-confirmed infection during outbreak of pandemic (H1N1) 2009, England*

Variable AOR (95% CI) for ARI in questionnaire sample AOR (95% CI) for positive test result in matched sample
Age group, y
13–15 1 1
16–18 1.57 (0.98–2.53) 1.85 (0.95–3.60)
20–49 1.00 (0.53–1.89) 0.30 (0.12–0.73)
0.66 (0.32–1.34)
0.20 (0.08–0.53)
Took antiviral drugs for PEP†
No 1
0.41 (0.27–0.61)
0.55 (0.30–0.99)
Seasonal Influenza vaccine
No 1 1
Yes 1.01 (0.63–1.62) 1.81 (0.91–3.59)

*For ARI, n = 654 who completed questionnaires; for serology-confirmed infection, n = 333 who completed questionnaires and had a matched serology sample. ARI, acute respiratory infection; AOR, adjusted odds ratio; CI, confidence interval; PEP, postexposure prophylaxis.
†Persons who reported taking treatment dose of antiviral agents were excluded.

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