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Volume 17, Number 9—September 2011
Letter

Bocavirus in Children with Respiratory Tract Infections

Li Guo, Richard Gonzalez, Zhengde Xie, Hongli Zhou, Chunyan Liu, Chao Wu, Gláucia Paranhos-Baccalà, Guy Vernet, Kunling Shen, Qi Jin, and Jianwei WangComments to Author 
Author affiliations: Author affiliations: State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing, People’s Republic of China (L. Guo, Q. Jin, J. Wang); Institute of Pathogen Biology, Beijing (L. Guo, R. Gonzalez, H. Zhou, C. Wu, Q. Jin, J. Wang); Fondation Mérieux, Lyon, France (R. Gonzalez, G. Paranhos-Baccalà, G. Vernet); Beijing Children’s Hospital, Beijing (Z. Xie, C. Liu, K. Shen)

Main Article

Table

Distribution and clinical characteristics of HBoV species in 1,238 children with acute lower respiratory tract infections, Beijing, China, 2008–2010*

Parameters HBoV1 HBoV2 HBoV3
No. (%) positive
 131 (10.6)
 5 (0.4)
 5 (0.4)
Age range, mo 1–132 1–113 1–108
No. (%) patients <5 y of age 124 (94.7) 4 (80) 4 (80)
Age mean/median, mo
 19/12
 29.2/7.2
 30.4/12
M/F
 72/59
 3/2
 4/1
Clinical manifestations, no. (%)
Fever 78 (59.5) 3 (60) 3 (60)
Cough 131 (100) 5 (100) 5 (100)
Sputum production 115 (87.8) 4 (80) 3 (60)
Wheezing 65 (49.6) 3 (60) 4 (80)
Runny nose 46 (35.1) 2 (40) 1 (20)
Diarrhea 9 (6.9) 0 (0) 1 (20)
Mean ± SD leukocyte count, ×109/L
 9.4 ± 5.3
 7.56 ± 1.4
 13.45 ± 6.1
Co-detection in samples, no. (%)
Rhinovirus 58 (44.3) 1 (20) 2 (40)
Respiratory syncytial virus 42 (32.1) 2 (40) 2 (40)
Parainfluenza virus 24 (18.3) 0 (0) 1 (20)
Influenza virus 11 (8.4) 1 (20) 2 (40)
Conorovirus 15 (11.5) 0 0
Adenovirus 14 (10.7) 0 1 (20)
Human metapneumovirus 16 (12.2) 0 0
Enterovirus 2 (1.5) 1 (20) 0

*Detection rate for HBoV species, χ2 = 234.1, p <0.01. No HBoV4 was found. HBoV, human bocavirus.

Main Article

Page created: September 06, 2011
Page updated: September 06, 2011
Page reviewed: September 06, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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