William R. Faber
, Rick Hoekzema, Aldert Bart, Jim E. Zeegelaar, and Henry J.C. de Vries
Figure. A) Crustosus plaque on the nose of the patient. B) The epidermis shows parakeratosis, atrophy, and a single apoptotic keratinocyte. An inflammatory infiltrate is present in the papillary dermis, mainly composed of (epithelioid) histiocytes, admixed with lymphocytes and few plasma cells. Most macrophages in the infiltrate are parasitized by numerous Leishmania spp. amastigotes (hematoxylin and eosin stain, original magnification ×400).