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Volume 18, Number 11—November 2012
Research

Lack of Cross-protection against Bordetella holmesii after Pertussis Vaccination

Xuqing Zhang, Laura S. Weyrich, Jennie S. Lavine, Alexia T. Karanikas, and Eric T. HarvillComments to Author 
Author affiliations: The Pennsylvania State University, University Park, Pennsylvania, USA

Main Article

Figure 6

Supplementation of whole-cell pertussis vaccine (wP) with B. holmesii- but not B. pertussis- specific antibodies. Groups of four wP-vaccinated C57BL/6 mice were left untreated (none) or treated with naive serum, wP-induced sereum, or whole-cell Bordetella holmesii vaccine (wH)–induced serum, and challenged with B. holmesii. Bacterial numbers in the lungs on day 3 postinoculation are shown. Error bars indicate SE. *p<0.05.

Figure 6. . . . Supplementation of whole-cell pertussis vaccine (wP) with B. holmesii- but not B. pertussis- specific antibodies. Groups of four wP-vaccinated C57BL/6 mice were left untreated (none) or treated with naive serum, wP-induced sereum, or whole-cell Bordetella holmesii vaccine (wH)–induced serum, and challenged with B. holmesii. Bacterial numbers in the lungs on day 3 postinoculation are shown. Error bars indicate SE. *p<0.05.

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Main Article

Page created: October 15, 2012
Page updated: October 15, 2012
Page reviewed: October 15, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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