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Volume 18, Number 12—December 2012
Dispatch

Arctic-like Rabies Virus, Bangladesh

Khondoker Mahbuba Jamil, Kamruddin AhmedComments to Author , Moazzem Hossain, Takashi Matsumoto, Mohammad Azmat Ali, Sohrab Hossain, Shakhawat Hossain, Aminul Islam, Mohammad Nasiruddin, and Akira Nishizono
Author affiliations: Author affiliations: Institute of Epidemiology, Disease Control, and Research, Dhaka, Bangladesh (K.M. Jamil); Oita University, Oita, Japan (K. Ahmed, T. Matsumoto, A. Nishizono); Ministry of Health and Family Welfare, Dhaka (M. Hossain); Dhaka City Corporation, Dhaka (M.A. Ali, S. Hossain, A. Islam, M. Nasiruddin); Tongi Municipality, Tongi, Bangladesh (S. Hossain)

Main Article

Table 2

Substitutions in genome sequence of rabies virus BDR5 from Bangladesh compared with genome sequence of strain from India (AY956319)*

Protein, amino acid substitution Site/domain/region of protein†
N

Asp378 → Glu378

 Antigenic site IV

Gln422 → Arg422

 –
P

Ser64 → Pro64

 Variable domain I

Gln71 → Thr71

 Variable domain I

Asn90 → Ser90

 N protein binding site in variable domain II

Pro159 → Ser159

 N protein binding site in variable domain II

His162 → Ser162

 N protein binding site in variable domain II

Asn166 → Ser166

 N protein binding site in variable domain II

Ala174 → Val174

 N protein binding site in variable domain II
M

Leu21 → Pro21

 –

Ser46 → Gly46

 –

Ile168 →Val168

 –
G

Ala-(minus)15 → Val-15

 Signal peptide

Val-(minus)6 → Phe-6

 Signal peptide

Val7 → Ile7

 –

Asp146 → Asn146

 Putative additional N-glycosylation: NKS

Val427 → Ile427

 –

Arg462 → Gly462

 Transmembrane domain

His465 → Arg465

 Transmembrane domain

Gly473 → Ser473

 Transmembrane domain
L

Asp18 → Glu18

 –

Ala19 → Thr19

 –

Arg315 → Lys315

 Conserved domain I

Val361 → Leu361

 Conserved domain I

His640 → Gln640

 Conserved domain III

Lys657 → Arg657

 Conserved domain III

Ala966 → Thr966

 Conserved domain IV

Pro1133 → Ser1133

 Conserved domain V

Arg1307 Lys1307

 Conserved domain IV

Asp1373 → Gly1373

 –

Leu1626 → Val1626

 –

Leu1654 → Ser1654

 –

Val1755 → Ile1755

 –

Cys1825 → Tyr1825

 –

Asn1841 → Lys1841

 –

Gln1845 → His1845

 –

Cys1872 → Phe1872

 –

Asn2091 → Ser2091

 –

*N, nucleoprotein; P, phosphoprotein; M, matrix protein; G, glycoprotein; L, polymerase.
†– indicates that the amino acid substitution was in a location that has no site/domain/region name. NKS, asparagine-lysine-serine.

Main Article

Page created: November 20, 2012
Page updated: November 20, 2012
Page reviewed: November 20, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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