Volume 18, Number 2—February 2012
CME ACTIVITY - Research
Invasive Pneumococcal Disease and Pandemic (H1N1) 2009, Denver, Colorado, USA
George E. Nelson
, Kenneth A. Gershman, David L. Swerdlow, Bernard W. Beall, and Matthew R. Moore
, Kenneth A. Gershman, David L. Swerdlow, Bernard W. Beall, and Matthew R. Moore
Table 1
Epidemiologic characteristics of patients with invasive pneumococcal disease, Denver, Colorado, USA, February and October 2009*
| Characteristic | Patients with pandemic (H1N1) 2009, Oct 2009, n = 58 | Patients with seasonal influenza, Feb 2009, n = 45 | p value |
|---|---|---|---|
| Age, y | |||
| 0–<5 | 6 (10) | 0 (0) | NC |
| 5–19 | 3 (5) | 3 (7) | NC |
| 20–39 | 10 (17) | 6 (13) | NC |
| 40–59 | 26 (45) | 17 (38) | NC |
| >60 | 13 (22) | 19 (42) | NC |
| Median age (range 2 mo–91 y) | 45 | 54 | 0.02 |
| Sex | 0.120 | ||
| M | 38 (66) | 26 (58) | NC |
| F | 20 (34) | 16 (36) | NC |
| Unknown | 0 | 3 (7) | NC |
| Race† | 0.012 | ||
| White | 31 (53) | 11 (24) | NC |
| African American | 4 (7) | 3 (7) | NC |
| Asian | 0 (0) | 2 (4) | NC |
| Unknown | 23 (40) | 29 (64) | NC |
| Ethnicity† | <0.0001 | ||
| Hispanic | 14 (24) | 7 (16) | NC |
| Non-Hispanic | 25 (43) | 4 (9) | NC |
| Unknown | 19 (33) | 34 (76) | NC |
| Concurrent condition‡ | NC | ||
| Any | 40 (69) | 17 (38) | <0.0001 |
| Chronic lung disease | 17 (29) | 3 (7) | 0.0002 |
| Diabetes | 5 (9) | 6 (13) | 0.852 |
| HIV infection | 2 (3) | 0 (0) | 0.247 |
| Liver disease | 5 (8.6) | 2 (4) | 0.276 |
| Smoking | 15 (26) | 10 (22) | 0.669 |
| Hospitalized | |||
| Yes | 54 (93) | 36 (80) | 0.536 |
| No | 4 (7) | 2(4) | NC |
| Unknown | 0 | 7 (16) | NC |
| Tested for influenza§ | 47 (81) | NA | NC |
| Outpatient setting | 8 | NA | NC |
| Inpatient setting | 43 | NA | NC |
| Positive test result for influenza§ | 10 | NA | NC |
*Values are no. (%) unless otherwise indicated. NA, not available; NC, not calculated.
†Race and ethnicity data required additional patient consent.
‡Underlying concurrent condition comparisons were adjusted for age.
§Includes data from supplemental case report form not available for prior years.
Page created: January 26, 2012
Page updated: January 26, 2012
Page reviewed: January 26, 2012
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